Babak N Niknafs

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Phencyclidine (I) and its derivatives show such pharmacological behaviors as analgesic, anticonsulvant, anti-anxiety and antidepressant, while interacting with central nervous system. In this study, new methyl and hydroxyl derivatives of PCP were synthesized and their antinociceptive behaviors in animals were examined by measuring the number of writhing in(More)
Six benzimidazole derivatives, 5-Nitro-2-phenyl -1-ethyl benzimidazol (5), 2(p-Bromophenyl)5-nitro1ethyl benzimidazol (6), 2-(p-Bromophenyl-5-nitro-1–cyclopentyl benzimidazol (7), 2(p-Bromophenyl)-5nitro-1-cyclopentyl benzimidazol (8), 5-Amino-2-(p-Bromophenyl)-1-ethylbenzimidazol (9), and 5-Amino2-(p-Bromophenyl)-1-cyclopentyl benzimidazol (10) were(More)
OBJECTIVES The study attempted to investigate the anti-anxiety activities of Phencyclidine (1-(1-phenylcyclohexyl) piperidine, PCP, I) and some of its derivatives (M, F, L, B, S, P) with the elevated-plus maze (EPM) Test. MATERIAL AND METHODS Phencyclidine and its derivatives (M, F, L, B, S, P) were administrated intraperitoneally (i.p.) at a dose of 10(More)
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