Babak A. Vakili

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BACKGROUND Vulnerable plaque demonstrates intense inflammation in which macrophages secrete matrix metalloproteinases (MMPs) that degrade the fibrous cap, ultimately leading to rupture, in situ thrombosis, and an associated clinical event. Thus, inhibition of MMP activity or more general suppression of vascular inflammation are attractive targets for(More)
BACKGROUND To date there has been no comprehensive review of the association between left ventricular hypertrophy (LVH) at baseline and subsequent adverse clinical events. METHODS A total of 20 studies (with 48,545 participants) published between January 1960 and January 2000, identified through MEDLINE and other sources, related baseline(More)
OBJECTIVE To evaluate the incidence of urinary tract injury due to hysterectomy for benign disease. STUDY DESIGN Patients were enrolled prospectively from 3 sites. All patients undergoing abdominal, vaginal, or laparoscopic hysterectomy for benign disease underwent diagnostic cystourethroscopy. RESULTS Four hundred seventy-one patients participated.(More)
BACKGROUND Morbidity and mortality after an acute myocardial infarction (AMI) has been reported to be higher in women than men. However, in some prior reports, women were not treated as aggressively as men, suggesting a treatment bias. We sought to determine whether sex influenced short-term outcomes in a cohort of AMI patients, all of whom underwent(More)
OBJECTIVE To present the clinical, biochemical, and genetic features of a male pseudohermaphrodite whose condition was caused by 17beta-hydroxysteroid dehydrogenase 3 (17beta-HSD3) deficiency. DESIGN Case report. SETTING Gynecology practice in a university teaching hospital. PATIENT(S) A 15-year-old black American male pseudohermaphrodite with(More)
INTRODUCTION : To determine the attributes and motivation of physicians who pursue fellowship training in the subspecialties of Obstetrics and Gynecology (Ob/Gyn). METHODS : We surveyed current fellows and recent graduates from the ABOG recognized subspecialties in Ob/Gyn. Demographics and reasons for pursuing fellowship training were obtained.(More)
BACKGROUND An inverse relation exists between the number of coronary angioplasty procedures performed by physicians or hospitals and short-term mortality. It is not known, however, whether a similar relation holds for physicians and hospitals that perform primary angioplasty for acute myocardial infarction. METHODS AND RESULTS We analyzed data from the(More)
Oxygen-derived free radical formation can lead to cellular injury and death. Under normal situations, the human body has a free radical scavenger system (catalase, superoxide dismutase) that can detoxify free radicals. Antioxidant vitamins and enzymatic and synthetic oxygen-derived free radical scavengers have been used clinically to prevent the formation(More)
Vaginal evisceration of the bowel is a rare and life-threatening complication of gynecologic surgery; recurrence is even more rare. Most cases in the literature discuss primary closure of the dehisced vaginal cuff with delayed absorbable sutures via a vaginal, abdominal, or laparoscopic approach. The case presented here is of a patient who had a history of(More)