BS Nielsen

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Metastases are the major cause of cancer-related deaths, but the mechanisms of the metastatic process remain poorly understood. In recent years, the involvement of microRNAs (miRNAs) in cancer has become apparent, and the objective of this study was to identify miRNAs associated with breast cancer progression. Global miRNA expression profiling was performed(More)
Objective The receptor tyrosine kinase (RTK) Platelet-Derived Growth Factor Receptor a (PDGFRa) localizes to the primary cilium, and expression of the constitutive active PDGFRa D842V mutant has been linked to gastrointest-inal tumor formation. We set out to investigate whether expression of D842V causes loss of primary cilia in cultured cells. Methods(More)
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