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A 48-year-old man with a 27-year history of debilitating recurrent aphthous stomatitis major and pustular skin lesions was treated successfully with thalidomide. Side effects have not been encountered during a 6-month symptom-free period, while he has taken 25 mg per day. The drug is currently unavailable in this country except for the treatment of leprosy.(More)
Tumor marker screening by insurers is one of the most significant and controversial developments in insurance testing. The debate is ongoing. Key dimensions of the issue have been recently described.1,2 We do not wish to reiterate any of those dimensions, nor do we wish to comment favorably or unfavorably on tumor marker screening by insurers. Rather, we(More)
A panel of 10 mouse and rat monoclonal antibodies specific for different typeand group-specific O-antigenic determinants of Shigella flexneri lipopolysaccharide was used to serotype 240 isolates of S. flexneri from Bangladesh. Three immunoglobulin M antibodies were used in a direct slide agglutination test; seven immunoglobulin G antibodies were absorbed to(More)
Hereditary hemochromatosis has an autosomal recessive inheritance pattern. The homozygous diseased state occurs in 50 of 10,000 and the heterozygous non-diseased carrier state in 1000 of 10,000 caucasians.3 The typical case has two unaffected heterozygote carrier parents. However, HH can occur in consecutive generations owing to the chance mating between an(More)
Molecular Biology and Enteric Diseases Laboratories, Division of Bacterial Diseases, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 303331; Department of Microbiology and Immunology, The Norwegian College of Veterinary Medicine, Post Office Box 8146 DEP, 0033 Oslo 1, Norway2*; Division of Geographic Medicine, School of(More)
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