BH Bijnens

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BACKGROUND We sought to investigate ultrasonic strain rate and strain as new indices to quantify the contractile reserve of stunned myocardium during dobutamine infusion. METHODS AND RESULTS Stunning of the left ventricular posterior wall was induced in 9 closed-chest pigs after 30 minutes of severe hypoperfusion followed by 60 minutes of reperfusion of(More)
Techniques have been described in the literature to enable multidimensional strain rate estimation. They are based on multidimensional velocity estimation. One of the problems in obtaining robust lateral strain rate estimates is the fact that lateral velocity estimates are intrinsically noisier than axial ones. The aim of this study was to find the optimal(More)
A method to construct a Purkinje system automatically for a particular subject is presented. The system is grown using a rule-based algorithm controlled by stochastic and probabilistic decisions that determine the particular structure of the model. A set of user customizable parameters control the final structure, and allow obtaining realistic Purkinje(More)
Detecting changes in the contractility of the heart muscle, especially in the presence of coronary artery disease, is an important medical task. From isolated myocytes, it was suggested that chronic ischemia decreases but prolongs contraction. Additionally, severe aortic stenosis shows higher but often prolonged outflow velocities. From this, we hypothesize(More)
AIMS Positron emission tomographic imaging is known to be a reliable indicator of viable myocardium in chronic heart disease. Its value in acute myocardial infarction has not been studied extensively. METHODS AND RESULTS Sixty-two patients receiving thrombolytic therapy were studied. Myocardial tissue flow and metabolism were measured at 5 days and 3(More)
The dynamics of electrophysiological wave propagation in ventricular tissue are the result of a large number of interrelated processes. However there are applications in which a rough estimation of tissue activation time at a set of given points is sufficient. This paper presents a mesh-less method for fast calculation of the activation time at any(More)
Assessing myocardial function is a difficult task in clinical practice. Routinely, (systolic) cardiac function is mostly quantified based on ejection fraction, a measure of the volume fraction of the left ventricle being ejected with each cardiac cycle. However, this approach has a lot of limitations since normal ejection fraction can occur while there are(More)
The differentiation between differing regional ischaemic substrates is crucial for decision-making in patients with coronary artery disease. This study demonstrates that quantification of dobutamine stress echocardiography using ultrasonic strain measurement has the potential to identify three differing regional ischaemic substrates (ischaemic, stunned and(More)
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