Learn More
Cytokeratin polypeptides of human epidermis, of epithelia microdissected from various zones of the pilosebaceous tract (outer root-sheath of hair follicle, sebaceous gland), and of eccrine sweat-glands have been separated by one- and two-dimensional gel electrophoresis and characterized by binding of cytokeratin antibodies and by peptide mapping. The(More)
Patients with moderate to severe psoriasis are undertreated. To solve this persistent problem, the consensus programme was performed to define goals for treatment of plaque psoriasis with systemic therapy and to improve patient care. An expert consensus meeting and a collaborative Delphi procedure were carried out. Nineteen dermatologists from different(More)
Normal human epidermis, long since dismissed as merely a protective covering for the body, is now recognized as a complex immunological unit. This concept is based on the demonstration that Langerhans cells (LCs)t are potent APCs for a variety of T cell (TC) responses and that keratinocytes (KC), at least upon stimulation , can secrete a plethora of(More)
  • 1