• Publications
  • Influence
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.
TDP-43 is a predominantly nuclear RNA-binding protein that forms inclusion bodies in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). The mRNA targets of TDP-43 inExpand
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Orange: data mining toolbox in python
Orange is a machine learning and data mining suite for data analysis through Python scripting and visual programming. Here we report on the scripting part, which features interactive data analysisExpand
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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
In the nucleus of eukaryotic cells, nascent transcripts are associated with heterogeneous nuclear ribonucleoprotein (hnRNP) particles that are nucleated by hnRNP C. Despite their abundance, however,Expand
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Orange: From Experimental Machine Learning to Interactive Data Mining
Orange (www.ailab.si/orange) is a suite for machine learning and data mining. For researchers in machine learning, Orange offers scripting to easily prototype new algorithms and experimentalExpand
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Rule Evaluation Measures: A Unifying View
Numerous measures are used for performance evaluation in machine learning. In predictive knowledge discovery, the most frequently used measure is classification accuracy. With new tasks beingExpand
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Predictive data mining in clinical medicine: Current issues and guidelines
BACKGROUND The widespread availability of new computational methods and tools for data analysis and predictive modeling requires medical informatics researchers and practitioners to systematicallyExpand
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Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
Fused in sarcoma (FUS) and TAR DNA-binding protein 43 (TDP-43) are RNA-binding proteins pathogenetically linked to amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD),Expand
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Data Fusion by Matrix Factorization
  • M. Zitnik, B. Zupan
  • Computer Science, Mathematics
  • IEEE Transactions on Pattern Analysis and Machine…
  • 2 July 2013
For most problems in science and engineering we can obtain data sets that describe the observed system from various perspectives and record the behavior of its individual components. HeterogeneousExpand
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Spam Filtering Using Statistical Data Compression Models
Spam filtering poses a special problem in text categorization, of which the defining characteristic is that filters face an active adversary, which constantly attempts to evade filtering. Since spamExpand
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iCLIP Predicts the Dual Splicing Effects of TIA-RNA Interactions
Transcriptome-wide analysis of protein-RNA interactions predicts the dual splicing effects of TIA proteins, showing that their local enhancing function is associated with diverse distal splicingExpand
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