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Association between two genetic variants in miRNA and primary liver cancer risk in the Chinese population.
MicroRNAs (miRNAs) play an important role in the growth and development of human beings. Single nucleotide polymorphisms (SNPs) within miRNA could change their production or affinity with target… Expand
Genetic study of two single nucleotide polymorphisms within corresponding microRNAs and susceptibility to tuberculosis in a Chinese Tibetan and Han population.
MicroRNAs (miRNA) are thought to play important roles in the pathogenesis of diseases. Single nucleotide polymorphisms (SNPs) within miRNAs can change their characteristics via altering their target… Expand
Association of pre-microRNAs genetic variants with susceptibility in systemic lupus erythematosus
MicroRNAs (miRNAs) may play important roles in SLE, but genetic polymorphisms of miRNAs and their relationships with various autoantibodies present in SLE patients remain unclear. Here, we report… Expand
Precore Mutation of Hepatitis B Virus May Contribute to Hepatocellular Carcinoma Risk: Evidence from an Updated Meta-Analysis
Background Studies focused on the correlation of mutations in the genome of Hepatitis B Virus (HBV) like Pre-S mutation, Basal Core promoter (BCP), Enhancer II (EnhII), especially Precore mutation,… Expand
Molecular profile of drug resistance in tuberculous meningitis from southwest china.
- Lina Duo, B. Ying, +5 authors L. Wang
- Clinical infectious diseases : an official…
- 1 December 2011
BACKGROUND Tuberculous meningitis (TBM) is the most severe form of extrapulmonary tuberculosis and causes high mortality and morbidity. Isoniazid resistance is strongly predictive of death in… Expand
Association of polymorphisms in the human IL-10 and IL-18 genes with rheumatoid arthritis
The decrease of anti-inflammatory cytokine and increase of pro-inflammatory cytokine was observed in rheumatoid arthritis (RA). Interleukin-10 (IL-10), a potent anti-inflammatory cytokine, has been… Expand
Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways
Quercetin is a herbal flavonoid derived from various foods of plant origin and widely used as a major constituent of nutritional supplements. Quercetin has been shown to have anti-inflammatory… Expand
Association between promoter variants of interleukin-18 and schizophrenia in a Han Chinese population.
An increasing amount of evidence suggests that interleukin-18 (IL-18) plays a pivotal role in the pathophysiology of schizophrenia. However, association between single nucleotide polymorphism of… Expand
Association of HLA‐DP/DQ, STAT4 and IL‐28B variants with HBV viral clearance in Tibetans and Uygurs in China
- Yun Liao, B. Cai, +7 authors L. Wang
- Biology, Medicine
- Liver international : official journal of the…
- 1 March 2015
Several genome‐wide association studies have revealed that HLA‐DP/DQ, STAT4 and IL‐28B associated with liver diseases. But because of population heterogeneity, different races would have different… Expand
Quercetin attenuates airway inflammation and mucus production induced by cigarette smoke in rats.
- T. Yang, F. Luo, +11 authors Fuqiang Wen
- Chemistry, Medicine
- International immunopharmacology
- 1 May 2012
Mucus hypersecretion is a feature of many chronic airway diseases induced by cigarette smoke (CS), and evidence suggests that the antioxidant and anti-inflammatory flavonoid quercetin may protect… Expand