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Meningeal carcinomatosis in breast cancer.
Twenty-five breast cancer patients with meningeal carcinomatosis seen over a period of 16 months were reviewed. In all cases, the clinical diagnosis was made in the presence of diverse neurological… Expand
Cyclophosphamide, vincristine, adriamycin, and DTIC (CYVADIC) combination chemotherapy for the treatment of advanced sarcomas.
One hundred and forty adult patients with advanced sarcomas (125 soft tissue and 15 bone) were treated with a combination chemotherapy regimen consisting of cyclophosphamide, vincristine, Adriamycin,… Expand
Treatment for meningeal carcinomatosis in breast cancer
Forty breast cancer patients with meningeal carcinomatosis were treated with a combined program of whole brain irradiation therapy with intrathecal and intraventricular methotrexate and citrovorum… Expand
Meningeal carcinomatosis in breast cancer
Twenty‐five breast cancer patients with meningeal carcinomatosis seen over a period of 16 months were reviewed. In all cases, the clinical diagnosis was made in the presence of diverse neurological… Expand
Clinical pharmacology of IMPY by radioimmunoassay.
A radioimmunoassay for IMPY has been developed using [3H]acetyl-IMPY and antibody induced by immunizing rabbits with succinyl-IMPY bovine serum albumin conjugates. The method was reproducible and… Expand
Asparaginase and methotrexate combination chemotherapy in relapsed acute lymphoblastic leukemia in adults.
We have treated 37 adults with acute lymphoblastic leukemia (ALL), who have relapsed on previous intensive chemotherapy, with a combination of L-asparaginase and methotrexate (MTX) +/- ifosfamide.… Expand
Oropharyngeal candidiasis treated with a troche form of clotrimazole.
A randomized double-blind trial was conducted to assess the local effectiveness and safety of a troche form of clotrimazole in the treatment of oropharyngeal candidiasis in cancer patients. One half… Expand
Sarcoma of the stomach: Clinicopathologic study of 43 cases
The records of 43 patients with histologically proved primary gastric sarcoma treated at M. D. Anderson Hospital and Tumor Institute between 1945 and 1975 were reviewed. Weight loss, abdominal pain,… Expand
Infusion Chemotherapy for Soft Tissue Sarcomas
Adriamycin has formed the backbone of sarcoma chemotherapy since its introduction into clinical practice. The pioneering studies in this field by the late Dr. Jeffrey Gottlieb demonstrated modest but… Expand
Penetration of methylglyoxal bis(guanylhydrazone) into intracerebral tumors in humans.
- M. Rosenblum, D. Stewart, B. Yap, M. Leavens, R. Benjamin, T. Loo
- Cancer research
- 1 February 1981
Methylglyoxal bis(guanylhydrazone) (MGBG; NSC 32946) is currently being reevaluated for its clinical antineoplastic activity against both hematological and solid tumors. MGBG (100 to 200 mg/sq m) was… Expand