• Publications
  • Influence
[Effect of oxalysine on plasma fibrinogen content in tumor-bearing mice (author's transl)].
  • X. F. Yue, F. Wu, B. Xu
  • Chemistry, Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica…
  • 1 June 1982
Oxalysine (I-677) is a new antitumor antibiotic found in our laboratory. In tumor-bearing mice the plasma fibrinogen level was determined by Astrup’s method. The plasma fibrinogen was elevatedExpand
  • 3
  • 1
[Effect of oxalysine on pulmonary metastases of Lewis lung carcinoma in mice].
  • X. F. Yue, F. Wu, B. Xu
  • Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica…
  • 1 September 1985
Oxalysine was found to be an antitumor antibiotic with a simple chemical structure very similar to lysine. In this paper, the antimetastatic action of oxalysine was studied and compared withExpand
  • 3
  • 1
Inhibition of phosphorylation of histone H1 and H3 induced by 10-hydroxycamptothecin, DNA topoisomerase I inhibitor, in murine ascites hepatoma cells.
  • Y. Ling, B. Xu
  • Biology, Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica…
  • 1 November 1993
Hydroxycamptothecin (HCPT), isolated from Camptotheca acuminata, is a powerful antitumor alkaloid. Previous studies indicated that the molecular target of this agent was DNA topoisomerase I. TheExpand
  • 9
Anti-tumor effect of (S)-10-hydroxycamptothecin on mouse hepatoma BW7756 and its possible mode of action.
(S)-10-Hydroxycamptothecin (OPT), an analog of camptothecin (CPT), was found to inhibit the growth of the mouse hepatoma BW7756, when given at 1.0 mg/kg/day for 14 days. Cell cycle studies using flowExpand
  • 9
The influence of several anticancer agents on cell proliferation, differentiation and the cell cycle of murine erythroleukemia cells.
  • B. Xu
  • Biology, Medicine
  • The American journal of Chinese medicine
  • 1981
The influence of homoharringtonine, hydroxycamptothecin and lycobetaine on the cell cycle progression of murine erythroleukemia cells was studied by using flow microfluorometry (FMF) technique andExpand
  • 14
[Antimalarial effect and toxicity of methyl-dihydro-artemisinine in animals (author's transl)].
  • H. Gu, M. Liu, +6 authors R. Ji
  • Biology, Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica…
  • 1 June 1981
Methyl-dihydro-artemisinine (artemether) possessed higher efficacy against both Plasmodium berghei (both chloroquine sensitive and resistant strains) and P. cynomolgi than its parent compound,Expand
  • 10
[Inhibitory effect of hydroxycamptothecin on colony formation of KB cells and DNA damage].
Hydroxycamptothecin (HCPT) is an antitumor alkaloid isolated from Camptotheca acuminata Decaisne, a tree native to China. The present investigation showed that HCPT possesses strong cytotoxicity onExpand
  • 3
Suppression of the Obliteration Process by Ventilation in a Mouse Orthotopic Tracheal Transplantation Model
Background. Obliterative airway disease (OAD) has been a major obstacle to long-term survival after lung or tracheal transplantations, but the role of airflow has not been examined in the orthotopicExpand
  • 6
The effect of hydroxycamptothecin in the activity of RNA and DNA polymerases prepared from murine hepatoma cells.
  • B. Xu, Y. Ling
  • Biology, Medicine
  • The American journal of Chinese medicine
  • 1985
Hydroxycamptothecin (HCPT) is an antitumor alkaloid isolated from Camptotheca acuminata indigenous to China. It could reduce the activity of nuclear RNA polymerase II and I(III) of hepatoma cells.Expand
  • 4
[Distribution and excretion of 10-hydroxycamptothecin and its influence on immune response (author's transl)].
  • J. L. Yang, J. Han, B. Xu
  • Biology, Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica…
  • 1 September 1980
3H-hydroxycamptothecin was injected into the tail vein of mice in a dose of 10 mg/kg. The decline of radioactivity in the blood showed a biphasic curve. The first biological half-life(t1/2alpha) wasExpand
  • 5