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Angiotensin ii-(3–8)-hexapeptide affects motor activity, performance of passive avoidance and a conditioned avoidance response in rats
Angiotensin II-(3-8)-hexapeptide, at the dose of 1 nmol given intracerebroventricularly, only slightly less than angiotensin II (the same dose and route) stimulated exploratory locomotor behaviour inExpand
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Psychotropic effects of angiotensin II and III in rats: Locomotor and exploratory vs cognitive behaviour
One nmol of angiotensin II (AII) or angiotensin III (AIII) given intracerebroventricularly (i.c.v.) increased locomotor and exploratory activity in an open field apparatus but not in theExpand
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Behavioral effects of angiotensin II and angiotensin II-(4-8)-pentapeptide in rats
One nM of angiotensin II (AII) or angiotensin II-(4-8)-pentapeptide [AII(4-8)] given intracerebroventricularly did not affect locomotor and exploratory behavior of rats in open field. AIIExpand
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Effects of angiotensin II and its fragments: angiotensin II(3-8)-hexapeptide and angiotensin II(4-8)-pentapeptide on retrieval in passive avoidance situation in rats chronically treated with ethanol.
Rats with impaired retrieval of passive avoidance behavior induced by chronic (9 weeks) administration of ethanol were studied. Angiotensin II (AII) and its fragments: AII(3-8) and AII(4-8),Expand
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Angiotensin II--derived peptides devoid of phenylalanine in position 8 have full psychotropic activity of the parent hormone.
In this work we compared in rats the influence of heptapeptide 1-7-angiotensin II, hexapeptide 2-7-angiotensin II, pentapeptide 3-7-angiotensin II and angiotensin II on motility, stereotypy, learningExpand
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Cu(II) binding by angiotensin II fragments: Asp-Arg-Val-Tyr-Ile-His and Arg-Val-Tyr-Ile-His. Competition between amino group and imidazole nitrogens in anchoring of metal ions.
Potentiometric and spectroscopic (absorption, circular dichroism and electron paramagnetic resonance) study on the coordination of two angiotensin II fragments (Asp-Arg-Val-Tyr-Ile-His andExpand
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Antisera against three connexin43 fragments react with a 43-kD protein localised to gap junctions in myocardium and human myometrium.
Gap junctions are thought to play an essential role in the control of parturition. In this study we attempted to synthesise three short peptides which match the portion of the amino acid sequence ofExpand
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3-(p-Chlorophenyl)-4-aminobutanoic acid--resolution into enantiomers and pharmacological activity.
Racemic 3-(p-chlorophenyl)-4-aminobutanoic acid was resolved into enantiomers and their absolute configuration determined. Pharmacological activity of hydrochlorides of the racemic acid and itsExpand
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