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The growing burden of tuberculosis: global trends and interactions with the HIV epidemic.
The prevention of HIV and TB, the extension of WHO DOTS programs, and a focused effort to control HIV-related TB in areas of high HIV prevalence are matters of great urgency.
Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model
Estimates of world-wide distribution of child deaths from acute respiratory infections.
The Population Dynamics and Control of Tuberculosis
The changing relationship between the causative agent, Mycobacterium tuberculosis, and its human host is reviewed and a range of factors that could explain the persistence of TB are examined.
Drivers of tuberculosis epidemics: the role of risk factors and social determinants.
Natural History of Tuberculosis: Duration and Fatality of Untreated Pulmonary Tuberculosis in HIV Negative Patients: A Systematic Review
- E. Tiemersma, M. J. van der Werf, M. Borgdorff, B. Williams, N. Nagelkerke
- MedicinePloS one
- 4 April 2011
Current models of untreated tuberculosis that assume a total duration of 2 years until self-cure or death underestimate the duration of disease by about one year, but their case fatality estimates of 70% for smear-positive and 20% for culture-positive smear-negative tuberculosis appear to be satisfactory.
The Impact of Migration on HIV-1 Transmission in South Africa: A Study of Migrant and Nonmigrant Men and Their Partners
High rates of HIV were found among rural women, and the migration status of the regular partner was not a major risk factor for HIV.
The Potential Impact of Male Circumcision on HIV in Sub-Saharan Africa
If the results of that trial are confirmed, it is suggested that male circumcision could substantially reduce the burden of HIV in Africa, especially in southern Africa where the prevalence of MC is low and the prevalenceof HIV is high.
Tuberculosis among Health Care Workers
- I. Baussano, P. Nunn, B. Williams, E. Pivetta, M. Bugiani, F. Scano
- MedicineEmerging infectious diseases
- 1 March 2011
HCWs are at higher than average risk for TB, and sound TB infection control measures should be implemented in all health care facilities with patients suspected of having infectious TB.
Global incidence of multidrug-resistant tuberculosis.
These updated sets of estimates incorporating previously treated TB cases call for an urgent plan to expand appropriate diagnostic and treatment services for patients with MDR-TB in low-resource settings.