• Publications
  • Influence
The growing burden of tuberculosis: global trends and interactions with the HIV epidemic.
TLDR
The prevention of HIV and TB, the extension of WHO DOTS programs, and a focused effort to control HIV-related TB in areas of high HIV prevalence are matters of great urgency.
The Population Dynamics and Control of Tuberculosis
TLDR
The changing relationship between the causative agent, Mycobacterium tuberculosis, and its human host is reviewed and a range of factors that could explain the persistence of TB are examined.
Natural History of Tuberculosis: Duration and Fatality of Untreated Pulmonary Tuberculosis in HIV Negative Patients: A Systematic Review
TLDR
Current models of untreated tuberculosis that assume a total duration of 2 years until self-cure or death underestimate the duration of disease by about one year, but their case fatality estimates of 70% for smear-positive and 20% for culture-positive smear-negative tuberculosis appear to be satisfactory.
The Impact of Migration on HIV-1 Transmission in South Africa: A Study of Migrant and Nonmigrant Men and Their Partners
TLDR
High rates of HIV were found among rural women, and the migration status of the regular partner was not a major risk factor for HIV.
The Potential Impact of Male Circumcision on HIV in Sub-Saharan Africa
TLDR
If the results of that trial are confirmed, it is suggested that male circumcision could substantially reduce the burden of HIV in Africa, especially in southern Africa where the prevalence of MC is low and the prevalenceof HIV is high.
Tuberculosis among Health Care Workers
TLDR
HCWs are at higher than average risk for TB, and sound TB infection control measures should be implemented in all health care facilities with patients suspected of having infectious TB.
Global incidence of multidrug-resistant tuberculosis.
TLDR
These updated sets of estimates incorporating previously treated TB cases call for an urgent plan to expand appropriate diagnostic and treatment services for patients with MDR-TB in low-resource settings.
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