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2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Task Force on Expert Consensus Decision…
Role of P‐glycoprotein in Statin Drug Interactions
Drug interaction studies involving statins and digoxin support a role for P‐gp, an efflux protein located in the gastrointestinal tract, placenta, kidneys, brain, and liver, and many additional drugs such as diltiazem, verapamil, itraconazoles, ketoconazole, and cyclosporine, interact with statin and are modulators of both CYP3A4 and P‐ gp.
Recommendations for Management of Clinically Significant Drug-Drug Interactions With Statins and Select Agents Used in Patients With Cardiovascular Disease: A Scientific Statement From the American…
To optimize patient safety, healthcare providers must have an understanding of the mechanisms, magnitude, and potential consequences of any given DDI.
2018 ACC Expert Consensus Decision Pathway on Tobacco Cessation Treatment: A Report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents.
Argatroban for Prevention and Treatment of Thromboembolism in Heparin-Induced Thrombocytopenia
The use of argatroban in patients with HIT and HITTS is associated with improvement in clinical outcomes compared with historical controls, and it offers several practical advantages over other available agents with respect to dosing, monitoring, reversibility of effect with discontinuation of the drug, and cost.
Pharmacotherapy Considerations in Advanced Cardiac Life Support
Pharmacotherapy plays a role in the management of patients with cardiac arrest and treatment of electrolyte abnormalities, severe hypotension, pulmonary embolism, acute ischemic stroke, and toxicologic emergencies are important components of ACLS management.
Recommendations for Managing Drug–Drug Interactions with Statins and HIV Medications
- B. Wiggins, Donald G. Lamprecht, R. Page, J. Saseen
- Medicine, BiologyAmerican Journal of Cardiovascular Drugs
- 1 April 2017
With this understanding, the appropriate statin as well as statin dose can be selected in order to optimize the treatment of this patient population, while minimizing the potential risk of adverse effects.
Discharge Counseling for Patients with Heart Failure or Myocardial Infarction: A Best Practices Model Developed by Members of the American College of Clinical Pharmacy's Cardiology Practice and…
Key components of discharge counseling for patients with heart failure or myocardial infarction including medication use, medication dose and frequency, drug interactions, medications to avoid, common adverse effects, role of the medication in the disease state, signs and symptoms of the disease, diet, the patient's role in self‐care (lifestyle modifications), and when patients should seek medical advice are summarized.
Bivalirudin: A Direct Thrombin Inhibitor for Percutaneous Transluminal Coronary Angioplasty
Bivalirudin is a direct thrombin inhibitor that recently was approved as an alternative to heparin in patients undergoing PTCA and is being studied in comparison with unfractionated heparIn plus GP IIb‐IIIa receptor inhibitors in patients undergo intracoronary stent placement.