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The draft genome of a diploid cotton Gossypium raimondii
We have sequenced and assembled a draft genome of G. raimondii, whose progenitor is the putative contributor of the D subgenome to the economically important fiber-producing cotton species GossypiumExpand
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Unveiling the complexity of the maize transcriptome by single-molecule long-read sequencing
Zea mays is an important genetic model for elucidating transcriptional networks. Uncertainties about the complete structure of mRNA transcripts limit the progress of research in this system. Here,Expand
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Following a diabetogenic T cell from genesis through pathogenesis
Nonobese diabetic (NOD) mice spontaneously develop a disease very similar to type 1 diabetes in humans. We have generated a transgenic mouse strain carrying the rearranged T cell receptor genes fromExpand
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A heterozygous moth genome provides insights into herbivory and detoxification
How an insect evolves to become a successful herbivore is of profound biological and practical importance. Herbivores are often adapted to feed on a specific group of evolutionarily and biochemicallyExpand
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miR-200a Prevents Renal Fibrogenesis Through Repression of TGF-β2 Expression
OBJECTIVE Progressive fibrosis in the diabetic kidney is driven and sustained by a diverse range of profibrotic factors. This study examines the critical role of microRNAs (miRNAs) in the regulationExpand
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Cadmium and Its Neurotoxic Effects
  • B. Wang, Yanli Du
  • Biology, Medicine
  • Oxidative medicine and cellular longevity
  • 12 August 2013
Cadmium (Cd) is a heavy metal that has received considerable concern environmentally and occupationally. Cd has a long biological half-life mainly due to its low rate of excretion from the body.Expand
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Suppression of microRNA-29 expression by TGF-β1 promotes collagen expression and renal fibrosis.
Synthesis and deposition of extracellular matrix (ECM) within the glomerulus and interstitium characterizes renal fibrosis, but the mechanisms underlying this process are incompletely understood. TheExpand
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TGF-β Regulates miR-206 and miR-29 to Control Myogenic Differentiation through Regulation of HDAC4
MicroRNAs (miRs) are emerging as prominent players in the regulation of many biological processes, including myogenic commitment and skeletal muscle formation. Members of the TGF-β family canExpand
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Role of microRNA‐155 at early stages of hepatocarcinogenesis induced by choline‐deficient and amino acid–defined diet in C57BL/6 mice
MicroRNAs (miRs) are conserved, small (20‐25 nucleotide) noncoding RNAs that negatively regulate expression of messenger RNAs (mRNAs) at the posttranscriptional level. Aberrant expression of certainExpand
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Early microbial and metabolomic signatures predict later onset of necrotizing enterocolitis in preterm infants
BackgroundNecrotizing enterocolitis (NEC) is a devastating intestinal disease that afflicts 10% of extremely preterm infants. The contribution of early intestinal colonization to NEC onset is notExpand
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