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Endoplasmic reticulum of animal cells and its organization into structural and functional domains.
These processes involved in the establishment and maintenance of an anisotropic distribution of ER-resident proteins and, thus, in the organization of the ER into functionally and morphologically different subregions are outlined. Expand
Stimulus-induced Phosphorylation of Vacuolar H+-ATPase by Protein Kinase A*
Salivary glands of the blowfly Calliphora vicina are used to suggest that subunit C binds to and serves as a substrate for protein kinase A and that this phosphorylation may be a regulatory switch for the formation of the active V1V0 holoenzyme. Expand
Molecular characterization and localization of the first tyramine receptor of the American cockroach (Periplaneta americana)
This study marks the first comprehensive molecular, pharmacological, and functional characterization of a tyramine receptor in the cockroach, isolated a complementary DNA that encodes a biogenic amine receptor from the American cockroach Periplaneta americana, viz., Peatyr1. Expand
Molecular and Pharmacological Characterization of Serotonin 5-HT2α and 5-HT7 Receptors in the Salivary Glands of the Blowfly Calliphora vicina
This study represents the first comprehensive molecular and pharmacological characterization of two 5-HT receptors in the blowfly and permits the analysis of the physiological role of these receptors, even when co-expressed in cells, and of the modes of interaction between the Ca2+- and cAMP-signalling cascades. Expand
Elemental distribution in Rana pipiens retinal rods: quantitative electron probe analysis.
The composition of dark‐adapted and illuminated retinal rod outer and inner segments and mitochondria was determined with electron probe X‐ray micro‐analysis of cryosections and Mitochondrial Na and Mg paralleled the changes in the cytoplasmic concentrations. Expand
Calcium-sequestering smooth endoplasmic reticulum in retinula cells of the blowfly.
  • B. Walz
  • Biology, Medicine
  • Journal of ultrastructure research
  • 1 November 1982
The photoreceptor cells of the blowfly, Calliphora erythrocephala, have been shown to contain a well-developed network of subrhabdomeric (=submicrovillar) smooth endoplasmic reticulum (SER) cisternae, which suggest that the SER participates in the control of cytosolic free Ca 2+ in the submicromolar concentration range. Expand
Distribution and serotonin-induced activation of vacuolar-type H+-ATPase in the salivary glands of the blowfly Calliphora vicina
Biochemical assays provided evidence that the serotonin-induced activation of V-ATPase activity was accompanied by a recruitment of peripheral V1 subunits from the cytosol to the plasma membrane, indicative of the assembly of V0V1 holoenzymes, which might constitute a regulatory mechanism for the control of pump activity. Expand
The blowfly salivary gland - a model system for analyzing the regulation of plasma membrane V-ATPase.
The blowfly salivary glands are a superior and exemplary system for the analysis of the intracellular signaling pathways and mechanisms that modulate V-ATPase activity and solute transport in an insect epithelium. Expand
The mechanism mediating regenerative intercellular Ca2+ waves in the blowfly salivary gland
The results demonstrate that propagation of agonist‐evoked Ca2+ waves in the blowfly salivary gland requires supra‐basal [InsP3] but does not depend on feedback activation of phospholipase C. Expand
cAMP regulates plasma membrane vacuolar-type H+-ATPase assembly and activity in blowfly salivary glands.
These findings suggest that the cAMP pathway mediates the reversible assembly and activation of V-ATPase molecules at the apical membrane upon hormonal stimulus. Expand