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Synthetic bio-nanoreactor: mechanical and chemical control of polymersome membrane permeability.
The biodistribution of maltotriose modified poly(propylene imine) (PPI) dendrimers conjugated with fluorescein—proofs of crossing blood–brain–barrier
Oligosaccharide-modified poly(propylene imine) dendrimers are promising candidates as drug carriers and as anti-prion agents. Here, we report the biodistribution of maltotriose-modified 4th… Expand
Hyperbranched and highly branched polymer architectures--synthetic strategies and major characterization aspects.
“Life is branched” was the motto of a special issue of Macromolecular Chemistry and Physics1 on “Branched Polymers”, indicating that branching is of similar importance in the world of synthetic… Expand
The influence of densely organized maltose shells on the biological properties of poly(propylene imine) dendrimers: new effects dependent on hydrogen bonding.
Maltose-modified poly(propylene imine) (PPI) dendrimers were synthesized by reductive amination of unmodified second- to fifth-generation PPI dendrimers in the presence of excess maltose. The… Expand
Cross-linked polymersomes as nanoreactors for controlled and stabilized single and cascade enzymatic reactions.
Polymeric vesicles or polymersomes are one of the supramolecular entities at the leading edge of synthetic biology. These small compartments have shown to be feasible candidates as nanoreactors,… Expand
Cytotoxicity of PAMAM, PPI and maltose modified PPI dendrimers in Chinese hamster ovary (CHO) and human ovarian carcinoma (SKOV3) cells
Characterization of dendrimers as potential therapeutics or drug carriers is complete only when toxicity is assessed. There are numerous studies on the influence of surface modification of PAMAM and… Expand
Genotoxicity of poly(propylene imine) dendrimers.
- B. Ziemba, Gabriela Matuszko, D. Appelhans, B. Voit, M. Bryszewska, B. Klajnert
- Chemistry, Medicine
- 1 August 2012
Dendrimers are highly branched macromolecules with the potential in biomedical applications. Due to positively charged surfaces, several dendrimers reveal toxicity. Coating peripheral cationic groups… Expand
Smart cellulose/graphene composites fabricated by in situ chemical reduction of graphene oxide for multiple sensing applications
Cellulose/graphene nanocomposite films are prepared by dispersing graphene oxide (GO) and dissolving cellulose homogeneously in alkaline–urea aqueous solution followed by in situ chemical reduction… Expand
Ethoxysilyl-modified hyperbranched polyesters as mulitfunctional coupling agents for epoxy-silica hybrid coatings
Abstract Partially ethoxysilyl-modified hyperbranched aliphatic–aromatic polyesters (HBPs) were effectively used as toughening as well as multi-site coupling agents in the preparation of… Expand