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Differential expression of gonadotropin and prolactin antigens by GHRH target cells from male and female rats.
There is a 2- to 3-fold increase in luteinizing hormone-beta (LHbeta) or follicle-stimulating hormone-beta (FSHbeta) antigen-bearing gonadotropes during diestrus in preparation for the peak LH or FSHExpand
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Cytochemical detection of gonadotropin-releasing hormone-binding sites on rat pituitary cells with luteinizing hormone, follicle-stimulating hormone, and growth hormone antigens during diestrous
Pituitary cells with GnRH receptors increase over 2-fold during diestrus to reach a peak during the morning of proestrus. This is followed by a rapid fall during the afternoon of proestrus to reach aExpand
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Progastrin1-80 stimulates growth of intestinal epithelial cells in vitro via high-affinity binding sites.
  • P. Singh, X. Lu, +4 authors A. Owlia
  • Biology, Medicine
  • American journal of physiology. Gastrointestinal…
  • 1 February 2003
Proliferation and carcinogenesis of the large intestinal epithelial cells (IEC) cells is significantly increased in transgenic mice that overexpress the precursor progastrin (PG) peptide. It is notExpand
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Differential effects of inhibin on gonadotropin stores and gonadotropin-releasing hormone binding to pituitary cells from cycling female rats.
Numerous studies of rat pituitaries have reported that inhibin suppresses the synthesis and release of FSH and decreases the release of LH. The latter effect seems to be related to theExpand
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Topographical mapping of GnRH receptors on dispersed mouse pituitary cells by backscattered electron imaging
Mouse anterior pituitary cells cultured for 2 days were stimulated with one of three biotinylated‐GnRH probes ([biotinyl‐Lys6]‐[D‐Lys6]GnRH, [biotinyl‐Ser4]‐[D‐Lys6]GnRH, [biotinyl‐Ser4]‐[D‐Trp6,Expand
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Statins and downstream inhibitors of the isoprenylation pathway increase type 2 iodothyronine deiodinase activity.
The type 2 iodothyronine selenodeiodinase (D2) is a critical determinant of local thyroid signaling, converting T(4) to the active form T(3) at the cytoplasmic face of the endoplasmic reticulum, thusExpand
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Change in Body Mass Index After Breast Reconstruction and Associated Complications
Objective: The incidence and prevalence of breast cancer continue to rise. Therapies may contribute to patient weight gain. Obesity, a major predictor of surgical complications, may affectExpand
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Thyroid Hormone at Near Physiologic Concentrations Acutely Increases Oxygen Consumption and Extracellular Acidification in LH86 Hepatoma Cells.
Thyroid hormone (T3) has been known to regulate the basal metabolic rate for more than a century, but mechanistic understanding is lacking both at the level of the intact organism and in terms of howExpand
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