• Publications
  • Influence
The molecular basis of Turcot's syndrome.
BACKGROUND Turcot's syndrome is characterized clinically by the concurrence of a primary brain tumor and multiple colorectal adenomas. We attempted to define the syndrome at the molecular level. Expand
  • 1,053
  • 50
Laparoscopic sentinel node mapping in early-stage cervical cancer.
OBJECTIVE We aimed to determine the feasibility and accuracy of sentinel node (SN) mapping and its ability to predict the status of the regional nodal basin. METHODS From October 2000 to SeptemberExpand
  • 189
  • 11
Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in
Uridine diphospho-glucuronosyltransferases (UGTs) inactivate and facilitate the excretion of estrogens to glucuronides (-G), the most abundant circulating estrogen conjugates. The identity of theExpand
  • 187
  • 9
  • PDF
Markers of radioresistance in squamous cell carcinomas of the head and neck: a clinicopathologic and immunohistochemical study.
PURPOSE The lack of accurate criteria to predict the response to radiotherapy for individual patients with squamous cell carcinoma of the head and neck (HN-SCC) remains a major problem. The purposeExpand
  • 130
  • 8
Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients.
PURPOSE Many cancer patients take antioxidant vitamin supplements with the hope of improving the outcome of conventional therapies and of reducing the adverse effects of these treatments. AExpand
  • 209
  • 8
Diagnosis of urothelial carcinoma from urine
  • B. Tětu
  • Medicine
  • Modern Pathology
  • 29 May 2009
Urine cytology is the most widely used noninvasive test to detect urothelial tumors. However, it is limited by its low sensitivity. On the other hand, cystoscopy is the gold standard procedure toExpand
  • 118
  • 8
The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis
IntroductionMatrix metalloproteinase (MMP)-2 is very active at degrading extracellular matrix. It is under the influence of an activator, membrane type 1 MMP (MMP-14), and the tissue inhibitor ofExpand
  • 117
  • 8
The early clinical course of primary Ta and T1 bladder cancer: a proposed prognostic index.
OBJECTIVE To develop a simple prognostic index for anticipating more precisely the early clinical course of primary superficial bladder cancer. PATIENTS AND METHODS The prognostic value of patientExpand
  • 137
  • 7
Immunocytochemical Localization of Type 5 17 β-Hydroxysteroid Dehydrogenase in Human Reproductive Tissues
17β-hydroxysteroid dehydrogenase (17β-HSD) controls the last step in the formation of all androgens and all estrogens. At least six 17β-HSD isoenzymes have been identified. The recently cloned Type 5Expand
  • 100
  • 7
Updated recommendations from the Canadian National Consensus Meeting on HER2/neu testing in breast cancer
Testing for her2/neu in breast cancer at the time of primary diagnosis is now the standard of care. Accurate and standardized testing methods are of prime importance to ensure the properExpand
  • 67
  • 7
  • PDF