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Tamoxifen-loaded lecithin organogel (LO) for topical application: Development, optimization and characterization.
Lecithin organogels (LOs) are semi-solid systems with immobilized organic liquid phase in 3-D network of self-assembled gelators. This paper attempts to study the various attributes of LOs, startingExpand
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QbD-driven development and evaluation of nanostructured lipid carriers (NLCs) of Olmesartan medoxomil employing multivariate statistical techniques
Abstract Purpose: This research work entails quality by design (QbD)-based systematic development of nanostructured lipid carriers (NLCs) of Olmesartan medoxomil (OLM) with improved biopharmaceuticalExpand
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Genetic susceptibility of glutathione S‐transferase genes (GSTM1/T1 and P1) to coronary artery disease in Asian Indians
Genetic polymorphisms in glutathione S‐transferase (GST) genes may modulate the risk of cardiovascular diseases. The objective of present study was to investigate the potential association betweenExpand
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Long-chain triglycerides-based self-nanoemulsifying oily formulations (SNEOFs) of darunavir with improved lymphatic targeting potential
Abstract The current studies entail systematic development of SNEOFs containing long-chain triglycerides for improving lymphatic targeting of darunavir for complete inhibition of HIV progression. AsExpand
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Stimuli Responsive In Situ Gelling Systems Loaded with PLGA Nanoparticles of Moxifloxacin Hydrochloride for Effective Treatment of Periodontitis
The objectives of the present research work were systematic development of novel in situ gel formulation containing nanoparticles for localised delivery of moxifloxacin against bacterialExpand
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Development and characterization of single step self-assembled lipid polymer hybrid nanoparticles for effective delivery of methotrexate
The present study was designed to develop methotrexate (MTX) loaded lipid polymer hybrid nanoparticles (LPHNPs) for spatial and controlled delivery of this drug. LPHNPs were formulated by single stepExpand
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Phospholipid‐based formulation with improved attributes of coal tar
Purpose  The aim of this study was to evaluate the formulation characteristics and pharmacodynamic activity of the lecithinized coal tar formulation (LCT) employing different methodologies andExpand
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Niosome-based hydrogel of resveratrol for topical applications: An effective therapy for pain related disorder(s).
The present work endeavors for development and evaluation of resveratrol loaded niosomal hydrogel system for its anti-inflammatory action. Niosomes were prepared by thin film hydration and etherExpand
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Recent advances in galactose-engineered nanocarriers for the site-specific delivery of siRNA and anticancer drugs.
Galactosylated nanocarriers have recently emerged as viable and versatile tools to deliver drugs at an optimal rate specifically to their target tissues or cells, thus maximizing their therapeuticExpand
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Efficacy of Novel Topical Liposomal Formulation of Cyclosporine in Mild to Moderate Stable Plaque Psoriasis: A Randomized Clinical Trial.
IMPORTANCE Attempts to use topical cyclosporine in treatment of psoriasis have failed because of unfavorable physicochemical properties and inappropriate formulation design of the conventional dosageExpand
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