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Increased expression of miR-222 is associated with poor prognosis in bladder cancer
TLDR
miR-222 overexpression is involved in the poor prognosis of bladder cancer and can be used as a biomarker for selection of cases requiring special attention. Expand
Testicular hypofunction caused by activating p53 expression induced by reactive oxygen species in varicocele rats
TLDR
It is demonstrated that varicocele caused hypoxia that could cause the rise of ROS level to induce the increase of p53 expression, leading to the decrease of testis mass index and changes of seminiferous tubules, which would reduce sperm motility and result in male infertility eventually. Expand
Identification of hub genes and pathways associated with bladder cancer based on co-expression network analysis.
TLDR
5 hub genes were successfully identified (LGALS4, PTPRN2, TMPRSS11E, TRIM31 and KCND3) and 5 biological pathways that may be underlying biomarkers for early diagnosis and treatment associated with bladder cancer were revealed. Expand
Identification of potential novel differentially-expressed genes and their role in invasion and migration in renal cell carcinoma
TLDR
An integrative bioinformatics approach is employed to identify ccRCC-related DEGs and associated signaling pathways, potentially helping to identify novel therapeutic targets for the treatment of this deadly disease. Expand
Expression profiles of variation integration genes in bladder urothelial carcinoma.
TLDR
The control mechanism underlying bladder cancer phenotype expression regulation by the major bladder cancer genes is explored and a series of modules associated with the terms 'cancer' or 'bladder' were considered to constitute a potential network. Expand
Quercetin protects against chronic prostatitis in rat model through NF‐κB and MAPK signaling pathways
TLDR
The therapeutic effect of quercetin is verified on Chronic Prostatitis/Chronic Pelvic Pain Syndrome and the mechanism responsible for it is identified. Expand
DLX1, a binding protein of beta‐catenin, promoted the growth and migration of prostate cancer cells
TLDR
It is demonstrated that DLX1 exerted the oncogenic roles on the prostate cancer by activating beta‐catenin/TCF signaling. Expand
Clinical characteristics and pathology of thyroid-like follicular carcinoma of the kidney: Report of 3 cases and a literature review
TLDR
Currently, TLFC has a relatively good prognosis; however, this conclusion requires further cases and long-term follow-ups, and improving the understanding of TLFC can help avoid misdiagnosis and prevent inappropriate treatment. Expand
The complete mitochondrial genome sequence of the prostate adenocarcinoma rat R3327
TLDR
This mitochondrial genome sequence will provide new genetic resource into prostate adenocarcinoma disease and is recognized as a suitable model for human prostate carcinoma. Expand
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