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Predominant Th2/Tc2 polarity of tumor-infiltrating lymphocytes in human cervical cancer.
- B. Sheu, R. H. Lin, H. C. Lien, H. N. Ho, S. Hsu, S. C. Huang
- Biology, Medicine
- Journal of immunology
- 1 September 2001
Cytotoxic T lymphocytes (Tc) play a central role in cellular immunity against cancers. The cytotoxic potential of freshly isolated tumor-infiltrating lymphocytes (TILs) is usually not expressed. This… Expand
A novel role of metalloproteinase in cancer-mediated immunosuppression.
Depressed immune responses have been observed frequently in cancer patients. In a variety of human malignancies, the expression of interleukin-2 receptor alpha (IL-2R alpha) on activated… Expand
Increased expression and activation of gelatinolytic matrix metalloproteinases is associated with the progression and recurrence of human cervical cancer.
Cancer-derived matrix metalloproteinases (MMPs) are proposed to be essential for tumor stromal invasion and subsequent metastasis. To explore the role of MMPs in cancer progression, we examined the… Expand
Cytokine regulation networks in the cancer microenvironment.
- B. Sheu, Wen-chun Chang, Chieh-Yang Cheng, Ho-Hsiung Lin, D. Chang, S. Huang
- Medicine, Biology
- Frontiers in bioscience : a journal and virtual…
- 1 May 2008
During carcinoma formation, cancer cells release various cytokines and growth factors into their surroundings and recruit and reprogram many other types of cells in order to establish a tumor… Expand
Standardized uptake value and apparent diffusion coefficient of endometrial cancer evaluated with integrated whole-body PET/MR: Correlation with pathological prognostic factors.
- I-Lun Shih, R. Yen, +13 authors T. Shih
- Journal of magnetic resonance imaging : JMRI
- 1 December 2015
PURPOSE To evaluate the correlation between maximum standardized uptake value (SUVmax ) and minimum apparent diffusion coefficient (ADCmin ) of endometrial cancer derived from an integrated positron… Expand
Clinical significance of tumor-infiltrating lymphocytes in neoplastic progression and lymph node metastasis of human breast cancer.
To investigate the clinical significance of tumor-infiltrating lymphocytes (TILs) within the tumor milieu, we quantitatively measured and compared the subpopulations of TILs in 24 patients with stage… Expand
Immune concept of human papillomaviruses and related antigens in local cancer milieu of human cervical neoplasia
- B. Sheu, Wen-chun Chang, Ho-Hsiung Lin, Song-Nan Chow, S. Huang
- The journal of obstetrics and gynaecology…
- 1 April 2007
It is presently the right time for clarifying human papillomavirus (HPV)‐associated cellular immunity and clinical implications before global HPV vaccination programs begin. Infection with oncogenic… Expand
Reversed CD4/CD8 ratios of tumor‐infiltrating lymphocytes are correlated with the progression of human cervical carcinoma
To investigate the clinical significance of tumor‐infiltrating lymphocytes (TILs) within the tumor milieu of human cervical carcinoma, the authors quantitatively measured and compared the… Expand
Importance of urodynamic study before radical hysterectomy for cervical cancer.
OBJECTIVES The aim of this study was to characterize the urodynamic findings in patients with cervical cancer before radical hysterectomy and to correlate the results with age, parity, menopausal… Expand
Intramural ectopic pregnancy
- H. Lu, B. Sheu, J. Shih, Y. Chang, P. Torng, S. C. Huang
- Acta obstetricia et gynecologica Scandinavica
- 1 September 1997
EEG, cranial CT, MRI, and EEG were all normal. Laboratory values showed a slight rise in serum cardiolipin IgCi antibodies, 6 unitsil (<3U/l) in April 1994, but two months after delivery they had… Expand