B. Seymour

Publications163
h-index48
Citations18,910
Highly Influential Citations1,276
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Empathy for Pain Involves the Affective but not Sensory Components of Pain
Our ability to have an experience of another's pain is characteristic of empathy. Using functional imaging, we assessed brain activity while volunteers experienced a painful stimulus and compared it… Expand
Cortical substrates for exploratory decisions in humans
Decision making in an uncertain environment poses a conflict between the opposing demands of gathering and exploiting information. In a classic illustration of this ‘exploration–exploitation’… Expand
Empathic neural responses are modulated by the perceived fairness of others
The neural processes underlying empathy are a subject of intense interest within the social neurosciences. However, very little is known about how brain empathic responses are modulated by the… Expand
Model-based influences on humans’ choices and striatal prediction errors
Summary The mesostriatal dopamine system is prominently implicated in model-free reinforcement learning, with fMRI BOLD signals in ventral striatum notably covarying with model-free prediction… Expand
Dopamine-dependent prediction errors underpin reward-seeking behaviour in humans
Theories of instrumental learning are centred on understanding how success and failure are used to improve future decisions. These theories highlight a central role for reward prediction errors in… Expand
Frames, Biases, and Rational Decision-Making in the Human Brain
Human choices are remarkably susceptible to the manner in which options are presented. This so-called “framing effect” represents a striking violation of standard economic accounts of human… Expand
When Fear Is Near: Threat Imminence Elicits Prefrontal-Periaqueductal Gray Shifts in Humans
Humans, like other animals, alter their behavior depending on whether a threat is close or distant. We investigated spatial imminence of threat by developing an active avoidance paradigm in which… Expand
Temporal difference models describe higher-order learning in humans
TLDR
We show that neural activity in the ventral striatum and the anterior insula displays a marked correspondence to the signals for sequential learning predicted by temporal difference models. Expand
Context-Dependent Human Extinction Memory Is Mediated by a Ventromedial Prefrontal and Hippocampal Network
In fear extinction, an animal learns that a conditioned stimulus (CS) no longer predicts a noxious stimulus [unconditioned stimulus (UCS)] to which it had previously been associated, leading to… Expand
Encoding of Marginal Utility across Time in the Human Brain
Marginal utility theory prescribes the relationship between the objective property of the magnitude of rewards and their subjective value. Despite its pervasive influence, however, there is… Expand
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