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Effectiveness and cost-effectiveness of a universal parenting skills programme in deprived communities: multicentre randomised controlled trial
Objective To evaluate the effectiveness and cost utility of a universally provided early years parenting programme. Design Multicentre randomised controlled trial with cost-effectiveness analysis.Expand
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Cost effectiveness of the NHS breast screening programme: life table model
Objective To assess the overall cost effectiveness of the NHS breast screening programme, based on findings of the Independent UK Panel on Breast Cancer Screening and taking into account theExpand
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A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre,
BACKGROUND Antibiotic-associated diarrhoea (AAD) occurs most commonly in older people admitted to hospital and within 12 weeks of exposure to broad-spectrum antibiotics. Although usually a mild andExpand
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Cost and Impact on Patient Length of Stay of Rapid Molecular Testing for Clostridium difficile
IntroductionA study was performed to assess the cost of a rapid molecular assay (PCR) for diagnosis of Clostridium difficile infection (CDI) and the impact of its routine use on patient length ofExpand
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Cost-e"ectiveness of interventions for chronic wound debridement: an evaluation in search of data
comprising a series of monthly treatment cycles over 12 months. Results: Initiating treatment with LDT is estimated to be a less costly and more effective debridement strategy than initiatingExpand
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Predictive risk stratification model: a progressive cluster-randomised trial in chronic conditions management (PRISMATIC) research protocol
BackgroundAn ageing population increases demand on health and social care. New approaches are needed to shift care from hospital to community and general practice. A predictive risk stratificationExpand
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General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE
BackgroundMost patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed an antibiotic, which may not always be appropriate and mayExpand
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PWE-008 Placide: Probiotics in the Prevention of Antibiotic Associated Diarrhoea (AAD) and Clostridium Difficile Associated Diarrhoea (CDD) in Elderly Patients Admitted to Hospital – Results of a
Introduction Antibiotic associated diarrhoea (AAD) and Clostridium difficile associated diarrhoea (CDD) occur in 5–39% of pts exposed to antibiotics. Despite previous papers proposing a beneficialExpand
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Prehospital recognition and antibiotics for 999 patients with sepsis: protocol for a feasibility study
BackgroundSepsis is a common condition which kills between 36,000 and 64,000 people every year in the UK. Early recognition and management of sepsis has been shown to reduce mortality and improve theExpand
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