• Publications
  • Influence
Neural correlates of the LSD experience revealed by multimodal neuroimaging
TLDR
Three complementary neuroimaging techniques, implemented during resting state conditions, revealed marked changes in brain activity after LSD that correlated strongly with its characteristic psychological effects, contributing important new insights into the characteristic hallucinatory and consciousness-altering properties of psychedelics.
Broadband Cortical Desynchronization Underlies the Human Psychedelic State
TLDR
The findings suggest that the subjective effects of psychedelics result from a desynchronization of ongoing oscillatory rhythms in the cortex, likely triggered by 5-HT2A receptor-mediated excitation of deep pyramidal cells.
Is it time to revisit the role of psychedelic drugs in enhancing human creativity?
  • B. Sessa
  • Psychology
    Journal of psychopharmacology
  • 28 February 2008
TLDR
There are similarities between the typical traits of creative people and the subjective psychological characteristics of the psychedelic (hallucinogenic) drug experience, and now may be the time to re-visit these studies with contemporary research methods.
A Review of 3,4-methylenedioxymethamphetamine (MDMA)-Assisted Psychotherapy
TLDR
Other potential therapeutic applications for MDMA therapy are described, including contemporary studies treating anxiety associated with autism and the authors' ongoing study exploring the potential role for MDMA-assisted psychotherapy to treat alcohol use disorder.
Can psychedelics have a role in psychiatry once again?
  • B. Sessa
  • Psychology
    The British journal of psychiatry : the journal…
  • 1 June 2005
Psychedelic or hallucinogenic drugs such as lysergic acid diethylamide (LSD), 3,4,5-trimethoxy-β-phenethylamine (mescaline), psilocybin, 3,4-methylenedioxymethamphetamine (MDMA),
A reconsideration and response to Parrott AC (2013) “Human psychobiology of MDMA or ‘Ecstasy’: an overview of 25 years of empirical research”
TLDR
Though it critiques an attempt by other authors to characterize the risks of MDMA, the review fails to produce a competing model of risk assessment, and does not discuss potential benefits, which may deter researchers from further investigating an innovative treatment.
The administration of psilocybin to healthy, hallucinogen-experienced volunteers in a mock-functional magnetic resonance imaging environment: a preliminary investigation of tolerability
TLDR
It is demonstrated that up to 2 mg of psilocybin delivered as a slow intravenous injection produces short-lived but typical drug effects that are psychologically and physiologically well tolerated.
Is there a case for MDMA-assisted psychotherapy in the UK?
  • B. Sessa
  • Psychology
    Journal of psychopharmacology
  • 18 October 2006
TLDR
The author asks that the medical profession consider a dispassionate and open-minded debate to examine whether MDMA might have a legitimate place as an adjunct to psychotherapy in modern psychiatric practice.
Why MDMA therapy for alcohol use disorder? And why now?
  • B. Sessa
  • Psychology, Medicine
    Neuropharmacology
  • 7 November 2017
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