B. Rumack

Publications274
h-index53
Citations12,555
Highly Influential Citations245
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2006 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS)
TLDR
NPDS represents a valuable national resource to collect and monitor US poisoning exposure cases, offers one of the few real-time surveillance systems in existence, provides useful data and is a model for public health surveillance.
Acetaminophen Hepatotoxicity: The First 35 Years
  • B. Rumack
  • Medicine, Biology
    Journal of toxicology. Clinical toxicology
  • 1 January 2002
TLDR
The lack of enhancement of acetaminophen toxicity by phenytoin and in fact, the potential for reduction of toxicity with that agent is a good example of the evolution of knowledge.
Acetaminophen overdose. 662 cases with evaluation of oral acetylcysteine treatment.
TLDR
Acute alcohol use resulted in less severe toxic reactions than in those patients without acute alcohol use and those patients with no history of chronic alcohol use, and no consistent difference in hepatotoxicity could be demonstrated.
Acetaminophen poisoning and toxicity.
TLDR
Although toxicity and fatalities have occurred in the adolescent age group, only one death in younger children has been recorded and the question must be raised as to how many cases of "jaundice of unknown etiology" are actually due to this drug.
Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985)
TLDR
It is concluded that N-acetylcysteine treatment should be started within eight hours of an acetaminophen overdose, but that treatment is still indicated at least as late as 24 hours after ingestion, and it may be superior when treatment is delayed.
2011 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 29th Annual Report
TLDR
These data support the continued value of poison center expertise and need for specialized medical toxicology information to manage the more severe exposures, despite a decrease in calls involving less severe exposures.
2007 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 25th Annual Report
Background: This report is the 25th Annual Report of the American Association of Poison Control Centers (AAPCC; http://www.aapcc.org) National Poison Data System (NPDS). During 2007, 60 of the…
2010 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 28th Annual Report
TLDR
These data support the continued value of poison center expertise and need for specialized medical toxicology information to manage the more severe exposures, despite a decrease in calls involving less severe exposures.
Ibuprofen overdose: 126 cases.
TLDR
In this study of ibuprofen overdose, symptoms developed in 19% of patients (24 of 126)--in 7% of children (6 of 88) and in 47% of adults (18 of 38)--in both the symptomatic and asymptomatic groups.
Acetaminophen overdose: a 48-hour intravenous N-acetylcysteine treatment protocol.
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