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Bioactive diterpenes from Orthosiphon labiatus and Salvia africana-lutea.
The known (+)-trans-ozic acid (1) and two new labdane diterpenoids (2 and 3) have been isolated from an ethanol extract of Orthosiphon labiatus. The structures of 2 and 3 were established mainly byExpand
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Analgesic, anti-inflammatory, antipyretic and haematological effects of aethiopinone, an o-naphthoquinone diterpenoid from Salvia aethiopis roots and two hemisynthetic derivatives.
Aethiopinone (1), an o-naphthoquinone diterpene from Salvia aethiopis L. roots and two hemisynthetic derivatives 2 and 3 have been evaluated for toxicity, anti-inflammatory, analgesic, antipyretic,Expand
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Antimycobacterial Metabolites from Plectranthus: Royleanone Derivatives against Mycobacterium tuberculosis Strains
The antimycobacterial activities of eight diterpenes, 1–8, isolated previously from Plectranthus and eleven esters, 9–19, of 7α‐acetoxy‐6β,12‐dihydroxyabieta‐8,12‐diene‐11,14‐dione (5) were evaluatedExpand
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A complete 1H and 13C NMR data assignment for four drimane sesquiterpenoids isolated from Drimys winterii
From the bark of Drimys winterii Forst., the drimane derivatives drimendiol, polygodial, isotadeonal and isodrimeninol were isolated. Complete and unambiguous 1H and 13C NMR chemical shiftExpand
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Abietanes from Plectranthus grandidentatus and P. hereroensis against methicillin- and vancomycin-resistant bacteria.
The antimicrobial activity of 10 natural abietanes isolated from Plectranthus grandidentatus and P. hereroensis acetonic extract was evaluated against methicillin-resistant Staphylococcus aureusExpand
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Structure and antimicrobial activity of diterpenes from the roots of Plectranthus hereroensis.
Two abietane-type diterpenoids have been isolated from the roots of Plectranthus hereroensis (Labiatae), one being the already known horminone [1] and the other a new substance, 7Expand
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Tyrosinase activity of Greyia flanaganii (Bolus) constituents.
Hyper-pigmentation of the skin is a common problem that is prevalent in middle aged and elderly people. It is caused by over production of melanin. Tyrosinase is known to be the key enzyme in melaninExpand
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Effect of abietane diterpenes from Plectranthus grandidentatus on the growth of human cancer cell lines.
Five known abietane diterpenes, fatty acid esters of 7alpha-acyloxy-6beta-hydroxyroyleanone (1), grandidone A (2), 7alpha-acetoxy-6beta-hydroxyroyleanone (3), 6beta,7alpha-dihydroxyroyleanone (4),Expand
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Neoclerodane and labdane diterpenoids from Plectranthus ornatus.
Three new diterpenoids, a neoclerodane and two labdane derivatives, have been isolated from an acetone extract of Plectranthus ornatus. The structures of these compounds (plectrornatins A-C, 1-3,Expand
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1H and 13C NMR spectral assignments and conformational analysis of 14 19‐nor‐neoclerodane diterpenoids
Unambiguous and complete assignments of 1H and 13C NMR chemical shifts for 14 19‐nor‐neoclerodane diterpenoids, nine of them isolated from natural sources and five other synthetic derivatives, areExpand
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