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Non-clinical pharmacology and safety evaluation of TH9507, a human growth hormone-releasing factor analogue.
- E. Ferdinandi, P. Brazeau, K. High, B. Procter, S. Fennell, P. Dubreuil
- Basic & clinical pharmacology & toxicology
TH9507, an analogue of human growth hormone-releasing factor (hGRF1-44NH2) minimally modified by addition of a trans-3-hexenoyl moiety to Tyr1 of the amino acid sequence, was found to be resistant to… Expand
Subchronic toxicity studies of sucrose acetate isobutyrate (SAIB) in the rat and dog.
Preliminary short-term toxicity studies of sucrose acetate isobutyrate (SAIB) in the dog demonstrated that addition of this additive to the diet was associated with an increase in liver size and… Expand
Experimental studies on acute and chronic action of azelastine on nasal mucosa in guinea pigs, rats and dogs.
- U. Achterrath-Tuckermann, K. Berthold, +5 authors M. Herbst
- 1 November 1997
Azelastine (CAS 37932-96-0) nasal spray (Allergodil, Rhinolast, Astelin) was investigated in acute experiments in guinea pigs and after a 26-week local application period with daily repeated… Expand