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Comprehensive Assessment of Transcriptional Regulation Facilitates Metabolic Engineering of Isoprenoid Accumulation in Arabidopsis1[OPEN]
- I. Lange, B. Poirier, Blake K Herron, B. M. Lange
- Environmental Science, BiologyPlant Physiology
- 17 August 2015
It is demonstrated that the overexpression of predictable combinations of genes can be used to significantly enhance flux toward specific end products of the sterol pathway.
Integrative Approaches for the Identification and Localization of Specialized Metabolites in Tripterygium Roots1[OPEN]
- B. M. Lange, J. Fischedick, Malte F. Lange, N. Srividya, D. Šamec, B. Poirier
- BiologyPlant Physiology
- 18 November 2016
This work employed an approach that involves the searching of multiple, complementary chromatographic and spectroscopic data sets against the Spektraris database to speed up the metabolite identification process and provides first insights into the cell type specificity of metabolite accumulation in Tripterygium.
Temporal Dynamics of the Soil Metabolome and Microbiome During Simulated Anaerobic Soil Disinfestation
Novel potential modes of disease control during ASD were identified and the importance of the amendment and “community metabolism” for temporally supplying specific classes of labile compounds were revealed.
Differential Partitioning of Triterpenes and Triterpene Esters in Apple Peel.
- B. Poirier, D. Buchanan, D. Rudell, J. Mattheis
- ChemistryJournal of agricultural and food chemistry
- 14 February 2018
Two separate metabolic analyses of isolated wax fractions and peel epidermis are reported to investigate the spatial distribution of secondary metabolites in peel to identify several unreported fatty acid esters of ursane-type triterpenes.
Misexpression of the Niemann-Pick disease type C1 (NPC1)-like protein in Arabidopsis causes sphingolipid accumulation and reproductive defects
Main conclusionMisexpression of theAtNPC1-1andAtNPC1-2genes leads to altered sphingolipid metabolism, growth impairment, and male reproductive defects in a hemizygousArabidopsis thaliana(L.)…
bHLH093/NFL and bHLH061 are required for apical meristem function in Arabidopsis thaliana
Results indicate that b HLH093 and bHLH061 function in the gibberellin-mediated establishment of functional apical meristems during the transition from vegetative to reproductive growth.
Integrative Approaches for the Identi fi cation and Localization of Specialized Metabolites in Tripterygium Roots 1 [ OPEN ]
Members of the genus Tripterygium are known to contain an astonishing diversity of specialized metabolites. The lack of authentic standards has been an impediment to the rapid identification of such…
Extending ‘Granny Smith’ apple superficial scald control following long-term ultra-low oxygen controlled atmosphere storage
A convergence of sunlight and cold chain: The influence of sun exposure on postharvest apple peel metabolism
Optimizing a High Performing Multiplex-CRISPRi P. putida Strain with Integrated Metabolomics and 13C-Metabolic Flux Analyses
Analysis of a 14-gene edited Pseudomonas putida KT2440 strain for heterologous indigoidine production provided actionable DBTL targets as well as insights into physiological responses and flux buffering when new recombineering tools were used.