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The FAB: A frontal assessment battery at bedside
The Frontal Assessment Battery is easy to administer at bedside and is sensitive to frontal lobe dysfunction.
The Mental Representation of Hand Movements After Parietal Cortex Damage
- A. Sirigu, J. Duhamel, L. Cohen, B. Pillon, Bruno Dubois, Y. Agid
- Psychology, BiologyScience
- 13 September 1996
Patients with lesions restricted to the parietal cortex were found to be impaired selectively at predicting, through mental imagery, the time necessary to perform differentiated finger movements and visually guided pointing gestures, in comparison to normal individuals and to a patient with damage to the primary motor area.
Bilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia.
- M. Vidailhet, L. Vercueil, P. Pollak
- Medicine, PsychologyThe New England journal of medicine
- 3 February 2005
These findings support the efficacy and safety of the use of bilateral stimulation of the internal globus pallidus in selected patients with primary generalized dystonia.
The neural system that bridges reward and cognition in humans: An fMRI study
- J. Pochon, R. Levy, B. Dubois
- Psychology, BiologyProceedings of the National Academy of Sciences…
- 16 April 2002
The study showed specific brain activation in relation with changes in both the cognitive loading and the reward associated with task performance, suggesting a balance between increasing activity in cortical cognitive areas and decreasing activity in the limbic and paralimbic structures during ongoing higher cognitive processing.
Neuropsychological changes between “off” and “on” STN or GPi stimulation in Parkinson’s disease
The specific effect of DBS seems to mimic the action of l-dopa treatment in the cognitive as in the motor domain, and the surgery associated with DBS does not appear to affect the cognitive performance of patients with PD 12 months later, except for a mild deficit in lexical fluency.
Cognitive deficits in Parkinson’s disease
Neuropsychological investigations of patients with Parkinson’s disease have shown specific impairments even in the early stages of the disease, which include deficit of behavioural regulation in sorting or planning tasks, defective use of memory stores, and impaired manipulation of internal representation of visuospatial stimuli, suggesting a functional continuity or complementarity between the basal ganglia and association areas of the prefrontal cortex.
Bilateral subthalamic or pallidal stimulation for Parkinson's disease affects neither memory nor executive functions: A consecutive series of 62 patients
It is concluded that stimulation of the subthalamic nucleus or internal globus pallidus does not change the overall cognitive performance in Parkinson's disease and does not greatly affect the functioning of subcorticofrontal loops involved in cognition in humans.
A frontal assessment battery at bedside
A short bedside cognitive and behavioral battery to assess frontal lobe functions is easy to administer at bedside and is sensitive to frontal lobe dysfunction.
Human autonomy and the frontal lobes. Part I: Imitation and utilization behavior: A neuropsychological study of 75 patients
Neuropsychological examination of patients with IB, of 35 with UB, and of 50 disease controls demonstrates the existence of a frontal syndrome and two determining features of such behavior: dependence on the social and the physical environments.
Relation of anosognosia to frontal lobe dysfunction in Alzheimer's disease.
- A. Michon, B. Deweer, B. Pillon, Y. Agid, B. Dubois
- PsychologyJournal of neurology, neurosurgery, and…
- 1 July 1994
The high correlation with the WCST score suggests that anosognosia in Alzheimer's disease is not related to the degree of cognitive deterioration but results, at least in part, from frontal dysfunction.