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Nitric Oxide Is Required for L-Type Ca2+ Channel-Dependent Long-Term Potentiation in the Hippocampus
Nitric oxide (NO) has long been implicated in the generation of long-term potentiation (LTP) and other types of synaptic plasticity, a role for which the intimate coupling between NMDA receptorsExpand
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On the selectivity of neuronal NOS inhibitors
Isoform‐selective inhibitors of NOS enzymes are desirable as research tools and for potential therapeutic purposes. Vinyl‐l‐N‐5‐(1‐imino‐3‐butenyl)‐l‐ornithine (l‐VNIO) and Nω‐propyl‐l‐arginine (NPA)Expand
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Cellular Targets of Nitric Oxide in the Hippocampus
In the hippocampus, as in many other CNS areas, nitric oxide (NO) participates in synaptic plasticity, manifested as changes in pre- and/or postsynaptic function. While it is known that these changesExpand
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Nitric oxide selectively suppresses IH currents mediated by HCN1‐containing channels
The superior olivary complex (SOC) exhibits a spectrum of HCN1 and HCN2 subunit expression, which generate IH currents with fast and slow kinetics, respectively. Neuronal nitric oxide synthase (nNOS)Expand
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Nitric oxide signalling in hippocampal synaptic plasticity
Nitric oxide (NO) is a freely diffusible transmitter acting throughout the mammalian nervous system via guanylyl cyclase activation and cGMP production. Since neuronal NO synthesis is linked to NMDAExpand
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Involvement of NO in NMDA receptor-independent long-term potentiation
Long-term potentiation (LTP) is a persistent increase in synaptic efficacy and, throughout the brain, a putative model of processes underlying learning and memory. Multiple forms of LTP exist withExpand
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