B. Pernow

Publications189
h-index47
Citations9,759
Highly Influential Citations98
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Substance P: a pioneer amongst neuropeptides
Abstract.   Hökfelt T, Pernow B, Wahren J (Karolinska Institutet, Stockholm, Sweden). Substance P: a pioneer amongst neuropeptides. J Intern Med 2001; 249: 27–40.
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Influence of age on the local circulatory adaptation to leg exercise.
Blood flow and oxygen uptake of the leg and release of lactate were studied in a group of 7 healthy well-trained 52–59-year-old men at rest and during bicycle exercise at work loads that were… Expand
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Substance p: localization in the central nervous system and in some primary sensory neurons
Antibodies to substance P with a high titer have been produced and used in immunohistochemical studies on the peripheral and central nervous system of the rat and the cat. Evidence was obtained for… Expand
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Flare and itch induced by substance P in human skin.
Intradermal injection of synthetic substance P (10(-7)--10(-5) M in humans produced flare, wheal and itching. These responses were inhibited by oral pretreatment of the subjects with an… Expand
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Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons
With the indirect immunofluorescence technique of Coons and collaborators the occurrence of substance P (SP)-like immunoreactivity was studied in spinal ganglia (L6-S1), the spinal cord (L6-S1) and… Expand
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Availability of glycogen and plasma FFA for substrate utilization in leg muscle of man during exercise
Summary. Six men performed two-legged cycle ergometer exercise at loads demanding 2–4 and 3–4 litres O2 min-1 (62 and 84% of Vo2 max) for 20 min each or to exhaustion twice with 1 h rest between. An… Expand
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Availability of substrates and capacity for prolonged heavy exercise in man.
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THE EFFECT OF LOCAL ANAESTHETICS ON THE CENTRAL CIRCULATION AND RESPIRATION IN MAN AND DOG1),2)
The effect on the central circulation and respiration of intravenously infused equipotent doses of mepivacaine and bupivacaine was studied in 11 healthy men and in four conscious dogs. The… Expand
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Uptake and release of free fatty acids and other metabolites in the legs of exercising men.
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Leg blood flow and muscle metabolism in occlusive arterial disease of the leg before and after reconstructive surgery.
1. Leg blood flow, uptake of oxygen and glucose and release of lactate by the leg and changes in intramuscular concentrations of metabolites were studied at rest and during exercise of increasing… Expand
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