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Apoptotic effect of quercetin on HT-29 colon cancer cells via the AMPK signaling pathway.
Activation of AMP-activated protein kinase (AMPK), a physiological cellular energy sensor, strongly suppresses cell proliferation in both nonmalignant and tumor cells. This study demonstrates theExpand
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Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in dogs.
A study on the bioavailability and pharmacokinetics of florfenicol was conducted in six healthy dogs following a single intravenous (i.v.) or oral (p.o.) dose of 20 mg kg(-1) body weight (b.w.).Expand
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Lipopolysaccharide-binding and neutralizing activities of surfactin C in experimental models of septic shock.
To evaluate the anti-endotoxin activity of surfactin C, we studied its lipopolysaccharide-binding activity in vitro and therapeutic efficacy in experimental models of gram-negative septic shock. TheExpand
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Plasma disposition of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, in rabbits after oral administration.
The objective of this study was to evaluate the pharmacokinetic profiles of toltrazuril (TZR), and its major metabolites toltrazuril sulfoxide (TZR x SO) and toltrazuril sulfone (TZR x SO(2)) inExpand
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Subacute (28 day) Toxicity of Surfactin C, a Lipopeptide Produced by Bacillus subtilis, in Rats
Surfactin C, produced by acillus subtilis isolated from Korean soybean paste, was given to Sprague-Dawley rats of both sexes at dose of 500, 1000 or 2000 mg/kg for 28 days. There were no surfactinExpand
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Production and physicochemical characterization of β-glucan produced byPaenibacillus polymyxa JB115
This study was conducted to develop a bacterial glucan as an animal feed additive. A novel glucan-producing bacterium.Paenibacillus polymyxa JB115, was isolated from Korean soil. The glucan,Expand
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The anti-thrombotic activity of surfactins.
Platelet aggregation was inhibited and the density of platelet-rich plasma (PRP) clots was decreased by the preincubation of PRP with surfactins, an acidic lipopeptide of Bacillus subtilis complexExpand
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Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs.
Toltrazuril (TZR) is a triazine-based antiprotozoal agent. Following a single oral administration of TZR at 10 and 20 mg/kg to male pigs, the mean TZR concentration in plasma peaked at 4.24 and 8.18Expand
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Plasma and tissue depletion of florfenicol in olive flounder (Paralichthys olivaceus) after oral administration
Abstract The aim of this study was to evaluate the pharmacokinetics of florfenicol after intravenous (i.v.) and oral (p.o.) administrations and investigate its depletion after multiple oralExpand
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Combination effects of cephalexin and gentamicin on Edwardsiella tarda and Streptococcus iniae.
The objective of this study was to determine the in vitro activity of cephalexin-gentamicin combination by a microbroth chequerboard technique against clinical isolates of Edwardsiella tarda andExpand
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