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The orexin system regulates alcohol‐seeking in rats
- A. Lawrence, M. Cowen, Hong-Ju Yang, Feng Chen, B. Oldfield
- Biology, MedicineBritish journal of pharmacology
- 1 July 2006
Re‐exposure of cues previously associated with alcohol availability is sufficient and adequate to activate orexin‐containing neurons and drive reinstatement of alcohol‐seeking in alcohol‐preferring rats.
The neurochemical characterisation of hypothalamic pathways projecting polysynaptically to brown adipose tissue in the rat
The sensory circumventricular organs of the mammalian brain.
- M. McKinley, R. McAllen, B. Oldfield
- Biology, MedicineAdvances in anatomy, embryology, and cell biology
- 5 August 2003
The brain's three sensory circumventricular organs, the subfornical organ, organum vasculosum of the lamina terminalis and the area postrema lack a blood brain barrier and are the only regions in the…
The brain renin-angiotensin system: location and physiological roles.
Gonadotropin-Inhibitory Hormone Is a Hypothalamic Peptide That Provides a Molecular Switch between Reproduction and Feeding
The dual effect on reproduction and feeding suggests that GnIH-3 provides a molecular switch between these two functions, and blockade of the positive feedback effect of estrogen with parenteral infusion indicates that this peptide may have utility as a blocker of reproductive function in mammals.
Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling
In spite of the increase in iBAT thermogenesis induced by GLP-1R activation in WT mice, Glp1r−/− mice exhibit a normal response to cold exposure, demonstrating that endogenous GLP 1R signaling is not essential for appropriate thermogenic response after cold exposure.
INTERACTION OF CIRCULATING HORMONES WITH THE BRAIN: THE ROLES OF THE SUBFORNICAL ORGAN AND THE ORGANUM VASCULOSUM OF THE LAMINA TERMINALIS
- M. McKinley, A. Allen, P. Burns, L. Colvill, B. Oldfield
- BiologyClinical and experimental pharmacology…
- 1 November 1998
Three of the CVO, the subfornical organ (SFO), organum vasculosum of the lamina terminalis (OVLT) and area postrema, contain neurons responsive to peptides such as angiotensin II (Angll), atrial natriuretic peptide and relaxin.
A comparison of hypotensive and non-hypotensive hemorrhage on Fos expression in spinally projecting neurons of the paraventricular nucleus and rostral ventrolateral medulla
The Role of Thermogenesis in Antipsychotic Drug‐induced Weight Gain
- A. Stefanidis, A. N. Verty, A. Allen, N. Owens, M. Cowley, B. Oldfield
- Psychology, MedicineObesity
- 1 January 2009
The anatomical studies provide an insight into the central neuroanatomical substrate that may subserve the altered thermogenic responses brought about by olanzapine, and show a significant impact of thermogenesis (and physical activity) on the weight gain associated with olanZapine treatment.
Efferent neural projections of angiotensin receptor (AT1) expressing neurones in the hypothalamic paraventricular nucleus of the rat.
- B. Oldfield, P. Davern, M. Giles, A. Allen, E. Badoer, M. McKinley
- BiologyJournal of neuroendocrinology
- 1 February 2001
The role that angiotensin II and AT1 receptors in the PVN may play in the mediation of responses to stress is highlighted.