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MALDI Imaging Mass Spectrometry Profiling of N-Glycans in Formalin-Fixed Paraffin Embedded Clinical Tissue Blocks and Tissue Microarrays
A recently developed matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) method to spatially profile the location and distribution of multiple N-linked glycan species inExpand
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  • 6
  • Open Access
Evaluation of 32 urine biomarkers to predict the progression of acute kidney injury after cardiac surgery
Biomarkers for acute kidney injury (AKI) have been used to predict the progression of AKI but a systematic comparison of the prognostic ability of each biomarkers alone or in combination has not beenExpand
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The 1.92-Å Structure of Streptomyces coelicolor A3(2) CYP154C1
  • L. Podust, Youngchang Kim, +7 authors M. Waterman
  • Medicine, Biology
  • The Journal of Biological Chemistry
  • 4 April 2003
Evolutionary links between cytochrome P450 monooxygenases, a superfamily of extraordinarily divergent heme-thiolate proteins catalyzing a wide array of NADPH/NADH- and O2-dependent reactions, areExpand
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  • 4
  • Open Access
Complementary Domain Prioritization: A Method to Improve Biologically Relevant Detection in Multi-Omic Data Sets
As the speed and quality of different analytical platforms increase, it is more common to collect data across multiple biological domains in parallel (i.e., genomics, transcriptomics, proteomics, andExpand
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  • 2
  • Open Access
Urinary angiotensinogen and risk of severe AKI.
BACKGROUND Biomarkers of AKI that can predict which patients will develop severe renal disease at the time of diagnosis will facilitate timely intervention in populations at risk of adverse outcomes.Expand
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  • Open Access
Urinary angiotensinogen predicts adverse outcomes among acute kidney injury patients in the intensive care unit
IntroductionAcute kidney injury (AKI) is commonly observed in the intensive care unit (ICU), where it can be caused by a variety of factors. The objective of this study was to evaluate the prognosticExpand
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Association of elevated urinary concentration of renin-angiotensin system components and severe AKI.
BACKGROUND Prognostic biomarkers that predict the severity of AKI at an early time point are needed. Urinary angiotensinogen was recently identified as a prognostic AKI biomarker. The studyExpand
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  • Open Access
Proteotranscriptomic Analysis Reveals Stage Specific Changes in the Molecular Landscape of Clear-Cell Renal Cell Carcinoma
Renal cell carcinoma comprises 2 to 3% of malignancies in adults with the most prevalent subtype being clear-cell RCC (ccRCC). This type of cancer is well characterized at the genomic andExpand
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  • Open Access
Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes*
Astrocytes and neurons form a highly specialized functional unit, and the loss or gain of astrocytic functions can influence the initiation and progression of different neurodegenerative diseases.Expand
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  • Open Access
Progress and Challenges in Ocean Metaproteomics and Proposed Best Practices for Data Sharing.
Ocean metaproteomics is an emerging field enabling discoveries about marine microbial communities and their impact on global biogeochemical processes. Recent ocean metaproteomic studies have providedExpand
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  • Open Access