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Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications.
Assessment of epithelial dysplasia in ulcerative colitis has been hindered by inconsistencies in and disagreements about nomenclature and interpretation. To resolve these issues, pathologists fromExpand
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Long-term risk of colorectal cancer after excision of rectosigmoid adenomas.
BACKGROUND AND METHODS Surveillance by repeated colonoscopy is currently recommended for patients with colorectal adenomas. We assessed the long-term risk of colorectal cancer after rigid-instrumentExpand
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The evolution of cancer of the colon and rectum
The malignant potential of adenomas of the colon and rectum varies with size, histological type and grade of epithelial atypia. The adenomatous polyp is usually small and has a low malignantExpand
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Juvenile polyposis–a precancerous condition
Clinical and pathological findings in 87 patients with juvenile polyposis have been reviewed; 1032 polyps were available from 80 of these patients; 840 were typical spherical juvenile polyps whereasExpand
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The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 cases
The grade of a tumour is gauged on the subjective assessment of a number of histopathological parameters. The problems associated with this exercise were viewed from a historical perspective andExpand
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Precancer and cancer in extensive ulcerative colitis: findings among 401 patients over 22 years.
Patients with extensive ulcerative colitis who do not need early surgery have been offered regular examination with the aim of detecting precancerous change (dysplasia) or early colorectal carcinoma.Expand
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Restorative proctocolectomy with ileal reservoir: pathological and histochemical study of mucosal biopsy specimens.
Mucosal biopsy specimens from the ileal reservoirs of 92 patients who had undergone restorative proctocolectomy (12 with familial adenomatous polyposis, 78 with ulcerative colitis, and two withExpand
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Rectal biopsy as an aid to cancer control in ulcerative colitis.
There is general agreement that malignant change in ulcerative colitis mostly occurs in those patients whose large intestine is totally involved and have a history of symptoms for more than 10 years.Expand
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The clinical significance of invasion of veins by rectal cancer
A histopathological study of 703 surgical specimens from patients with adenocarcinoma of the rectum revealed invasion of veins by primary growth in almost 52 per cent. Follow‐up studies on theExpand
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