• Publications
  • Influence
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
Ubiquitin-positive, tau- and α-synuclein–negative inclusions are hallmarks of frontotemporal lobar degeneration with ubiquitin-positive inclusions and amyotrophic lateral sclerosis. Although theExpand
  • 4,245
  • 539
  • PDF
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Several families have been reported with autosomal-dominant frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), genetically linked to chromosome 9p21. Here, we report an expansionExpand
  • 3,188
  • 297
  • PDF
Classification of primary progressive aphasia and its variants
This article provides a classification of primary progressive aphasia (PPA) and its 3 main variants to improve the uniformity of case reporting and the reliability of research results. Criteria forExpand
  • 2,471
  • 269
  • PDF
Frontotemporal lobar degeneration
Objective: To improve clinical recognition and provide research diagnostic criteria for three clinical syndromes associated with frontotemporal lobar degeneration. Methods: Consensus criteria for theExpand
  • 3,021
  • 193
  • PDF
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia.
Based on the recent literature and collective experience, an international consortium developed revised guidelines for the diagnosis of behavioural variant frontotemporal dementia. The validationExpand
  • 2,510
  • 139
  • PDF
Cognition and anatomy in three variants of primary progressive aphasia
We performed a comprehensive cognitive, neuroimaging, and genetic study of 31 patients with primary progressive aphasia (PPA), a decline in language functions that remains isolated for at least 2Expand
  • 1,166
  • 106
  • PDF
Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop.
Recent neuropathologic autopsy studies found that 15 to 25% of elderly demented patients have Lewy bodies (LB) in their brainstem and cortex, and in hospital series this may constitute the mostExpand
  • 1,681
  • 99
  • PDF
Neurodegenerative Diseases Target Large-Scale Human Brain Networks
During development, the healthy human brain constructs a host of large-scale, distributed, function-critical neural networks. Neurodegenerative diseases have been thought to target these systems, butExpand
  • 1,375
  • 56
  • PDF
Criteria for the diagnosis of corticobasal degeneration
Current criteria for the clinical diagnosis of pathologically confirmed corticobasal degeneration (CBD) no longer reflect the expanding understanding of this disease and its clinicopathologicExpand
  • 780
  • 55
  • PDF
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
Aspergillus fumigatus is exceptional among microorganisms in being both a primary and opportunistic pathogen as well as a major allergen. Its conidia production is prolific, and so human respiratoryExpand
  • 1,173
  • 54
  • PDF