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A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac
With the availability of complete genome sequence for Drosophila melanogaster, one of the next strategic goals for fly researchers is a complete gene knockout collection. The P-element transposon,Expand
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Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome
In fruit fly research, chromosomal deletions are indispensable tools for mapping mutations, characterizing alleles and identifying interacting loci. Most widely used deletions were generated byExpand
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LifeLines: visualizing personal histories
LifeLines provide a general visualization environment for personal histories that can be applied to medical and court records, professional histories and other types of biographical data. Expand
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Dynamic transcriptome of Schizosaccharomyces pombe shown by RNA-DNA hybrid mapping
We have determined the high-resolution strand-specific transcriptome of the fission yeast S. pombe under multiple growth conditions using a novel RNA-DNA hybridization mapping (HybMap) technique.Expand
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Molecular classification of melanoma using real‐time quantitative reverse transcriptase‐polymerase chain reaction
The early detection and characterization of metastatic melanoma are important for prognosis and management of the disease. Molecular methods are more sensitive in detecting occult lymph nodeExpand
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Reactive astrocytosis, microgliosis and inflammation in rats with neonatal hydrocephalus
The deleterious effects of hydrocephalus, a disorder that primarily affects children, include reactive astrocytosis, microgliosis and inflammatory responses; however, the roles that these mechanismsExpand
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Forkhead proteins control the outcome of transcription factor binding by antiactivation
Transcription factors with identical DNA‐binding specificity often activate different genes in vivo. Yeast Ace2 and Swi5 are such activators, with targets we classify as Swi5‐only, Ace2‐only, orExpand
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MicroRNAs and colon and rectal cancer: Differential expression by tumor location and subtype
MicroRNAs are thought to have an impact on cell proliferation, apoptosis, stress responses, maintenance of stem cell potency, and metabolism and are, therefore, important in the carcinogenic process.Expand
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Cellular electroporation induces dedifferentiation in intact newt limbs.
Newts have the remarkable ability to regenerate lost appendages including their forelimbs, hindlimbs, and tails. Following amputation of an appendage, the wound is rapidly closed by the migration ofExpand
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Zinc-dependent Regulation of the adh1 Antisense Transcript in Fission Yeast*
Background: Antisense transcription can inhibit complementary strand gene expression. Results: Multiple mechanisms ensure that adh1 antisense transcripts preferentially accumulate in zinc-limitedExpand
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