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- Publications
- Influence
Lignans From Forsythia x Intermedia Leaves and Flowers Attenuate the Pro-inflammatory Function of Leukocytes and Their Interaction With Endothelial Cells
- B. Michalak, A. Filipek, +7 authors A. Kiss
- Chemistry, Medicine
- Front. Pharmacol.
- 24 April 2018
Aim of the study: Taking into account that overactivated leukocytes are an important factor in the development of many chronic diseases, we investigated the activity of phytochemically characterized… Expand
Hydroxycinnamoyl derivatives and secoiridoid glycoside derivatives from Syringa vulgaris flowers and their effects on the pro-inflammatory responses of human neutrophils.
- M. Dudek, B. Michalak, +4 authors A. Kiss
- Chemistry, Medicine
- Fitoterapia
- 1 September 2017
Thirteen new compounds including caffeoyl-glucaric and p-coumaroyl-altraric acid derivatives, one monoterpenoid glucoside, four secoiridoid glycosides, and three hydroxycinnamoyl phenylpropanoid… Expand
Inula helenium and Grindelia squarrosa as a source of compounds with anti-inflammatory activity in human neutrophils and cultured human respiratory epithelium.
- B. Michalak, Wojciech Gierlikowski, Katarzyna Bekier, K. Skalicka-Woźniak, M. Czerwińska, A. Kiss
- Biology, Medicine
- Journal of ethnopharmacology
- 1 March 2020
ETHNOPHARMACOLOGICAL RELEVANCE
During the epidemic season, over 90% of acute wheezing disease is associated with bronchial inflammation. Both neutrophil- and eosinophil-mediated inflammation have… Expand
Inhibition of Pro‐Inflammatory Functions of Human Neutrophils by Constituents of Melodorum fruticosum Leaves
- N. Engels, B. Waltenberger, +4 authors H. Stuppner
- Chemistry, Medicine
- Chemistry & biodiversity
- 1 November 2018
In an initial screening, the dichloromethane extract from the leaves of Melodorum fruticosum showed distinct inhibitory effects on the release of interleukin‐8 (IL‐8) in human neutrophils. Therefore,… Expand
Effects of Phytochemically Characterized Extracts From Syringa vulgaris and Isolated Secoiridoids on Mediators of Inflammation in a Human Neutrophil Model
- M. Wożniak, B. Michalak, Joanna Wyszomierska, M. Dudek, A. Kiss
- Chemistry, Medicine
- Front. Pharmacol.
- 11 April 2018
Aim of the study: The aim of the present study was to investigate the effects of phytochemically characterized extracts connected with the traditional use (infusions and ethanolic extracts) of… Expand
Isolation of spilanthol from acmella oleracea based on green chemistry and evaluation of its in vitro anti-inflammatory activity
- Veronica Santana de Freitas Blanco, B. Michalak, +7 authors R. Rodrigues
- Chemistry
- 1 October 2018
Abstract Acmella oleracea (jambu) is a South American plant whose pharmacological properties include antimalarial, anesthetic, and anti-inflammatory activities. However, the compounds contributing to… Expand
UHPLC-DAD-ESI-MS/MS and HPTLC profiling of ash leaf samples from different commercial and natural sources and their in vitro effects on mediators of inflammation.
- A. Kiss, B. Michalak, Andrzej Patyra, M. Majdan
- Chemistry, Medicine
- Phytochemical analysis : PCA
- 2019
INTRODUCTION
In European traditional medicine, common ash leaf infusion is recommended by European Medicines Agency to treat minor articular pain and to increase the amount of urine for flushing… Expand
Carpesium divaricatum Sieb. & Zucc. Revisited: Newly Identified Constituents from Aerial Parts of the Plant and Their Possible Contribution to the Biological Activity of the Plant
- Natalia Kłeczek, B. Michalak, J. Malarz, A. Kiss, Anna Stojakowska
- Chemistry, Medicine
- Molecules
- 1 April 2019
Carpesium divaricatum Sieb. & Zucc. has a long history of use as both a medicinal and a food plant. However, except for terpenoids, its chemical constituents have remained poorly investigated. The… Expand
Syringa vulgaris bark as a source of compounds affecting the release of inflammatory mediators from human neutrophils and monocytes/macrophages
- A. Filipek, Joanna Wyszomierska, B. Michalak, A. Kiss
- Chemistry
- 1 April 2019
Abstract In traditional European medicine, common lilac (Syringa vulgaris L., Oleaceae) bark has been used in the form of an infusion, decoction or alcoholic extract as an antipyretic and a cold and… Expand