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Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura.
- J. Bussel, G. Cheng, +10 authors J. Jenkins
- MedicineThe New England journal of medicine
- 29 November 2007
Eltrombopag increased platelet counts in a dose-dependent manner in patients with relapsed or refractory ITP, and Bleeding also decreased during treatment in these two groups.
High body mass index is an independent predictor of differentiation syndrome in patients with acute promyelocytic leukemia.
- R. Jeddi, H. Ghedira, S. Mnif, E. Gouider, P. Fenaux, B. Meddeb
- MedicineLeukemia research
- 1 April 2010
Increased BMI has been correlated to an increased incidence of APL, but not to the occurrence of differentiation syndrome (DS) in APL; in multivariate analysis, BMI>or-30 remained an independent predictor of DS in addition to baseline WBC>or=20 x 10(9)/l.
Low dose prophylaxis in Tunisian children with haemophilia
- E. Gouider, L. Jouini, +4 authors B. Meddeb
- MedicineHaemophilia : the official journal of the World…
- 1 January 2017
Low dose prophylaxis could be recommended in countries with limited resources because of the high potential for underestimating the number of patients affected by infectious diseases.
[Surveillance of multidrug resistant bacteria in a Tunisian hospital].
- L. Thabet, A. Messadi, M. Mbarek, A. Turki, B. Meddeb, S. Ben Redjeb
- MedicineLa Tunisie medicale
- 1 November 2008
Antibiotic resistance evolution showed a decrease of resistance in 2006 versus 2005, which should be explained by the improvement of hygiene measure especially hand washing with the introduction of hydro- alcoholic solutions, a better targeted antibiotherapy promoted by a close cooperation between microbiologists and clinicians.
Predictive factors of all-trans-retinoic acid related complications during induction therapy for acute promyelocytic leukemia
High BMI (>35) in female and treatment without Cytarabine to increase the risk of developing complications with ATRA is found.
Megaloblastic anemia in North Africa.
Overall, 98% of patients had vitamin B12 deficiency and pernicious anemia accounted for most of these cases, and median age at presentation was 45 years.
Rituximab in combination with bendamustine or chlorambucil for the treatment of chronic lymphocytic leukemia: primary results from the randomised phase IIIb MABLE study
Factors associated with severe sepsis: prospective study of 94 neutropenic febrile episodes
Factors associated with the occurrence of severe sepsis were hypophosphatemia, heart rate/systolic blood pressure ratio, and non-adapted antibiotherapy at the onset of severe Sepsis, which were not predictive.
Risk factors of septic shock in patients with hematologic malignancies and Pseudomonas infections
Multivariate analysis revealed that hypophosphatemia, hypoproteinemia, and high serum lactate are significant factors, independently associated with increased risk of septic shock in patients with hematologic malignancies and Pseudomonas infections.
Safety and Efficacy of Long-Term Treatment with Oral Eltrombopag for Chronic Idiopathic Thrombocytopenic Purpura.
Oral eltrombopag is effective at raising platelet counts and decreasing bleeding symptoms during long-term treatment, regardless of splenectomy status or the use of baseline ITP medications.