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LDheatmap: An R Function for Graphical Display of Pairwise Linkage Disequilibria Between Single Nucleotide Polymorphisms
We describe the R function LDheatmap() which produces a graphical display, as a heat map, of pairwise linkage disequilibrium measurements between single nucleotide polymorphisms within a genomicExpand
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Large Sample Theory for Semiparametric Regression Models with Two-Phase, Outcome Dependent Sampling
Outcome-dependent, two-phase sampling designs can dramatically reduce the costs of observational studies by judicious selection of the most informative subjects for purposes of detailed covariateExpand
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hapassoc: Software for Likelihood Inference of Trait Associations with SNP Haplotypes and Other Attributes
Complex medical disorders, such as heart disease and diabetes, are thought to involve a number of genes which act in conjunction with lifestyle and environmental factors to increase diseaseExpand
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elrm: Software Implementing Exact-Like Inference for Logistic Regression Models
Exact inference is based on the conditional distribution of the sufficient statistics for the parameters of interest given the observed values for the remaining sufficient statistics. Exact inferenceExpand
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5‐Year Reoperation Rates After Different Types of Lumbar Spine Surgery
Study Design. Population‐based cohort study of Washington State patients who underwent lumbar spine surgery for degenerative conditions in 1988. Objectives. To compare complications and reoperationExpand
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A Note on Inference of Trait Associations with SNP Haplotypes and Other Attributes in Generalized Linear Models
Recently, Lake et al. [Human Heredity 2003;55:56–65] have proposed an approach based on the EM algorithm for maximum-likelihood inference of trait associations with haplotypes and environmentalExpand
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Stepwise detection of recombination breakpoints in sequence alignments
MOTIVATION We propose a stepwise approach to identify recombination breakpoints in a sequence alignment. The approach can be applied to any recombination detection method that uses a permutation testExpand
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IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5
In a large case-control study of Swedish incident type I diabetes patients and controls, 0–34 years of age, we tested the hypothesis that the GIMAP5 gene, a key genetic factor for lymphopenia inExpand
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Patient-Oriented Outcomes From Low Back Surgery: A Community-Based Study
Study Design. This study used a prospective cohort design. Objective To examine factors associated with favorable self-reported patient outcomes 1 year after elective surgery for degenerative backExpand
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Hospitalizations for back and neck problems: a comparison between the Province of Ontario and Washington State.
OBJECTIVE To examine back and neck hospitalizations in the Province of Ontario and Washington State. Because of their different organization and financing, there has been considerable interest inExpand
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