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Why there are complementary learning systems in the hippocampus and neocortex: insights from the successes and failures of connectionist models of learning and memory.
Damage to the hippocampal system disrupts recent memory but leaves remote memory intact. The account presented here suggests that memories are first stored via synaptic changes in the hippocampalExpand
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Path integration and the neural basis of the 'cognitive map'
The hippocampal formation can encode relative spatial location, without reference to external cues, by the integration of linear and angular self-motion (path integration). Expand
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Reactivation of hippocampal ensemble memories during sleep.
Simultaneous recordings were made from large ensembles of hippocampal "place cells" in three rats during spatial behavioral tasks and in slow-wave sleep preceding and following these behaviors. CellsExpand
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Theta phase precession in hippocampal neuronal populations and the compression of temporal sequences
O'Keefe and Recce [1993] Hippocampus 3:317–330 described an interaction between the hippocampal theta rhythm and the spatial firing of pyramidal cells in the CA1 region of the rat hippocampus: theyExpand
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Dynamics of the hippocampal ensemble code for space.
Ensemble recordings of 73 to 148 rat hippocampal neurons were used to predict accurately the animals' movement through their environment, which confirms that the hippocampus transmits an ensemble code for location. Expand
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Conjunctive Representation of Position, Direction, and Velocity in Entorhinal Cortex
Grid cells in the medial entorhinal cortex (MEC) are part of an environment-independent spatial coordinate system. Expand
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Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles
We used fluorescent in-situ hybridization and confocal microscopy to monitor the subcellular distribution of the immediate-early gene Arc. Arc RNA appeared in discrete intranuclear foci withinExpand
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Path Integration and Cognitive Mapping in a Continuous Attractor Neural Network Model
A minimal synaptic architecture is proposed for how the brain might perform path integration by computing the next internal representation of self-location from the current representation and from the perceived velocity of motion. Expand
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Hippocampal synaptic enhancement and information storage within a distributed memory system
Abstract The hypothesis that the physical substrate of memory in the mammalian brain resides in alterations of synaptic efficacy has been proposed frequently in both neuroscience 1–5 and cognitiveExpand
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Interpreting neuronal population activity by reconstruction: unified framework with application to hippocampal place cells.
We show that the theoretical values of the minimal achievable reconstruction errors quantify how accurately a physical variable is encoded in the neuronal population in the sense of mean square error, regardless of the method used for reading out the information. Expand
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