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Regulation of Notch Signaling by an Evolutionary Conserved DEAD Box RNA Helicase, Maheshvara in Drosophila melanogaster
- Satya Surabhi, B. Tripathi, B. Maurya, P. K. Bhaskar, Ashim Mukherjee, M. Mutsuddi
- Biology, Medicine
- 22 September 2015
Notch signaling is an evolutionary conserved process that influences cell fate determination, cell proliferation, and cell death in a context-dependent manner. Notch signaling is fine-tuned at… Expand
A loss‐of‐function homozygous mutation in DDX59 implicates a conserved DEAD‐box RNA helicase in nervous system development and function
We report on a homozygous frameshift deletion in DDX59 (c.185del: p.Phe62fs*13) in a family presenting with orofaciodigital syndrome phenotype associated with a broad neurological involvement… Expand
Maheshvara, a Conserved RNA Helicase, Regulates Notch Signaling in Drosophila melanogaster.
- B. Maurya, Satya Surabhi, Ashim Mukherjee, M. Mutsuddi
- Biology, Medicine
- Advances in experimental medicine and biology
Gene expression is regulated at multiple steps after generation of primary RNA transcripts, including mRNA processing, stability, and transport, along with co- and post-transcriptional regulation.… Expand
A biological observation on Stenobracon nicevillei (Bingham) (Braconidae: Hymenoptera), a larval parasitoid of sugarcane top borer.
Maheshvara regulates JAK/STAT signaling by interacting and stabilizing hopscotch transcripts which leads to apoptosis in Drosophila melanogaster
- B. Maurya, Satya Surabhi, Rituparna Das, P. Pandey, Ashim Mukherjee, M. Mutsuddi
- Cell death & disease
- 1 April 2021
Maheshvara (mahe), an RNA helicase that is widely conserved across taxa, regulates Notch signaling and neuronal development in Drosophila. In order to identify novel components regulated by mahe,… Expand
The Expanding Role of RNA-Binding Proteins in Neurodegeneration
In eukaryotic cells, gene expression is regulated at various levels after generation of a primary RNA transcript, including mRNA processing, transport, stability, and co-and post-transcriptional… Expand