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Hypertrophic cardiomyopathy: a systematic review.
TLDR
An appreciation that HCM, although an important cause of death and disability at all ages, does not invariably convey ominous prognosis and is compatible with normal longevity should dictate a large measure of reassurance for many patients.
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Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation…
TLDR
The present classification scheme recognizes the rapid evolution of molecular genetics in cardiology, as well as the introduction of several recently described diseases, and is unique in that it incorporates ion channelopathies as a primary cardiomyopathy.
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Sudden death in young competitive athletes. Clinical, demographic, and pathological profiles.
TLDR
Sudden death in young competitive athletes usually is precipitated by physical activity and may be due to a heterogeneous spectrum of cardiovascular disease, most commonly hypertrophic cardiomyopathy.
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Task Force on Sudden Cardiac Death of the European Society of Cardiology.
TLDR
The members of the Task Force on Sudden Death dedicate this paper to the memory of their former friend and colleague, Professor Ronald W. F. Campbell, who spent his life working in the field of sudden cardiac death, and the extent of the expanding knowledge in this field is described.
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Clinical profile of congenital coronary artery anomalies with origin from the wrong aortic sinus leading to sudden death in young competitive athletes.
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Congenital heart disease caused by mutations in the transcription factor NKX2-5.
TLDR
Data indicate that NKX2-5 is important for regulation of septation during cardiac morphogenesis and for maturation and maintenance of atrioventricular node function throughout life.
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2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice…
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Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary Artery Risk Development in (Young) Adults.
TLDR
These unique population-based data will aid in assessments of the impact of HCM-related mortality and morbidity in the general population and the practicality of screening large populations for HCM, including those comprising competitive athletes.
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Natural history and expansive clinical profile of stress (tako-tsubo) cardiomyopathy.
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Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy.
TLDR
In patients with hypertrophic cardiomyopathy, left ventricular outflow tract obstruction at rest is a strong, independent predictor of progression to severe symptoms of heart failure and of death.
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