• Publications
  • Influence
What is and what is not 'Fahr's disease'.
  • B. Manyam
  • Medicine, Psychology
  • Parkinsonism & related disorders
  • 1 March 2005
Bilateral almost symmetric calcification involving striatum, pallidum with or without deposits in dentate nucleus, thalamus and white matter is reported from asymptomatic individuals to a variety ofExpand
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Bilateral striopallidodentate calcinosis: Clinical characteristics of patients seen in a registry
Clinical features in bilateral striopallidodentate calcinosis (BSPDC), popularly referred to as Fahr's disease (five autosomal dominant families and eight sporadic cases, n = 38), recruited through aExpand
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Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification
Familial idiopathic basal ganglia calcification (IBGC) or Fahr's disease is a rare neurodegenerative disorder characterized by calcium deposits in the basal ganglia and other brain regions, which isExpand
  • 103
  • 10
  • Open Access
Neuroprotective mechanisms of ayurvedic antidementia botanical Bacopa monniera
Alzheimer's disease is a neurodegenerative disorder characterized by progressive dementia. Bacopa monniera is described in the Ayurvedic Materia Medica, as a therapeutically useful herb for theExpand
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  • 6
A randomized, double masked, controlled trial of botulinum toxin type A in essential hand tremor
Objective: To evaluate the safety and efficacy of botulinum toxin type A injection in essential tremor of the hand. Background: Botulinum toxin type A is an effective treatment for dystonia,Expand
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  • 5
Effect of antiparkinson drug HP‐200 (Mucuna pruriens) on the central monoaminergic neurotransmitters
HP‐200, which contains Mucuna pruriens endocarp, has been shown to be effective in the treatment of Parkinson's disease. Mucuna pruriens endocarp has also been shown to be more effective compared toExpand
  • 51
  • 5
Bacopa monniera extract reduces amyloid levels in PSAPP mice.
PSAPP mice expressing the "Swedish" amyloid precursor protein and M146L presenilin-1 mutations are a well-characterized model for spontaneous amyloid plaque formation. Bacopa monniera has a longExpand
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  • 4
Neuroprotective effects of the antiparkinson drug Mucuna pruriens
Mucuna pruriens possesses significantly higher antiparkinson activity compared with levodopa in the 6‐hydroxydopamine (6‐OHDA) lesioned rat model of Parkinson's disease. The present study evaluatedExpand
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Mucuna pruriens proves more effective than L‐DOPA in Parkinson's disease animal model
Seeds of the Mucuna pruriens plant, now known to contain L‐DOPA, have long been used for the treatment of Parkinson's disease patients in ancient Eastern Indian ethnotherapeutics. FollowingExpand
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A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease
Background: Creatine and minocycline were prioritized for testing in Phase II clinical trials based on a systematic evaluation of potentially disease modifying compounds for Parkinson disease (PD).Expand
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  • Open Access