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The role of saliva in tick feeding.
TLDR
This review will address the vertebrate mechanisms of these barriers as a guide to identify the possible targets of these large numbers of known salivary proteins with unknown function.
An annotated catalog of salivary gland transcripts from Ixodes scapularis ticks.
TLDR
Over 8000 expressed sequence tags from six different salivary gland cDNA libraries from the tick Ixodes scapularis support the hypothesis that gene duplication, most possibly including genome duplications, is a major player in tick evolution.
A review of Theileria diagnostics and epidemiology
TLDR
Serological and molecular assays exist for most economic important Theileria species and the concept of what constitute a Theilaria species impacts on accurate diagnostics.
The transcriptome of the salivary glands of the female western black-legged tick Ixodes pacificus (Acari: Ixodidae).
TLDR
106 mostly full-length sequences that clustered in 16 different families of tick proteins that may be useful for studying vascular biology or the immune system, for vaccine development, or as immunoreagents to detect prior exposure to ticks are reported.
An insight into the sialome of blood-feeding Nematocera.
TLDR
This review catalogs 1288 salivary proteins in 10 generic classes comprising over 150 different protein families, most of which the authors have no functional knowledge, and displays these proteins and many sequence comparisons in a hyperlinked spreadsheet that hopefully will stimulate and facilitate the task of functional characterization of these proteins.
Biochemical perspectives on paralysis and other forms of toxicoses caused by ticks
TLDR
This review considers the molecular nature of tick toxins, the possibility that tick toxins have originated more than once independently and whether these toxins could have unrecognized benign functions.
Nuttalliella namaqua: A Living Fossil and Closest Relative to the Ancestral Tick Lineage: Implications for the Evolution of Blood-Feeding in Ticks
TLDR
The data supports the monophyly of all tick families and suggests the evolution of argasid-like blood-feeding behaviour in the ancestral tick lineage and proposes an origin for ticks in the Karoo basin of Gondwanaland during the late Permian.
Comparative sialomics between hard and soft ticks: implications for the evolution of blood-feeding behavior.
TLDR
The ancestral tick may have possessed a simple (few members for each family), but diverse (many different protein families) salivary gland protein domain repertoire.
Comparative salivary gland transcriptomics of sandfly vectors of visceral leishmaniasis
TLDR
A comprehensive analysis of salivary proteins from female sandflies allowed the identification of genus- specific proteins, species-specific proteins and, more importantly, proteins common among these different sandflies.
Function, mechanism and evolution of the moubatin-clade of soft tick lipocalins.
  • B. Mans, J. Ribeiro
  • Biology, Medicine
    Insect biochemistry and molecular biology
  • 1 September 2008
TLDR
The data presented suggest that the ancestral function evolved in this clade was aimed at inhibition of vasoconstriction, platelet aggregation and neutrophil aggregation, primarily by scavenging of thromboxane A2 and leukotriene B4.
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