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CYP703 Is an Ancient Cytochrome P450 in Land Plants Catalyzing in-Chain Hydroxylation of Lauric Acid to Provide Building Blocks for Sporopollenin Synthesis in Pollen[W]
TLDR
Data demonstrate that in-chain hydroxy lauric acids are essential building blocks in sporopollenin synthesis and enable the formation of ester and ether linkages with phenylpropanoid units.
CYP704B1 Is a Long-Chain Fatty Acid ω-Hydroxylase Essential for Sporopollenin Synthesis in Pollen of Arabidopsis1[W][OA]
TLDR
It is shown that different classes of hydroxylated fatty acids serve as essential compounds for sporopollenin formation, and the genetic relationships between CYP704B1, CYP703A2, and another exine gene, MALE STERILITY2, which encodes a fatty acyl reductase, were explored.
Cyanogenic glycosides: synthesis, physiology, and phenotypic plasticity.
TLDR
It is important to understand the molecular mechanisms regulating cyanogenesis so that the impact of future environmental challenges can be anticipated and efforts are directed toward their removal to improve food safety.
Substrate specificity of plant UDP-dependent glycosyltransferases predicted from crystal structures and homology modeling.
TLDR
The accuracy and utility of UGT structures obtained by homology modeling are discussed and quantitative assessments of model quality are performed by modeling of a plant UGT for which the 3D crystal structure is known to conclude thathomology modeling offers a high degree of accuracy.
Improved vanillin production in baker's yeast through in silico design
TLDR
An in silico metabolic engineering strategy was designed using a set of stoichiometric modelling tools applied to the yeast genome-scale metabolic network that led to overproducing strains of vanillin producing S. cerevisiae strain.
Cassava Plants with a Depleted Cyanogenic Glucoside Content in Leaves and Tubers. Distribution of Cyanogenic Glucosides, Their Site of Synthesis and Transport, and Blockage of the Biosynthesis by RNA
TLDR
The data demonstrate that it is possible to drastically reduce the linamarin and lotaustralin content in cassava tubers by blockage of cyanogenic glucoside synthesis in leaves and petioles by RNA interference.
Metabolon formation and metabolic channeling in the biosynthesis of plant natural products.
TLDR
New experimental approaches document the importance of channeling in the synthesis of isoprenoids, alkaloids, phenylpropanoids, flavonoids and cyanogenic glucosides.
beta-Glucosidases as detonators of plant chemical defense.
TLDR
This review provides an update on knowledge of the beta-glucosidases involved in activation of the four major classes of phytoanticipins: cyanogenic glucosides, benzoxazinoid glucoside, avenacosides and glucosinolates.
De Novo Biosynthesis of Vanillin in Fission Yeast (Schizosaccharomyces pombe) and Baker's Yeast (Saccharomyces cerevisiae)
TLDR
These de novo pathways represent the first examples of one-cell microbial generation of these valuable compounds from glucose in S. pombe yeast and baker's yeast, as well as in Saccharomyces cerevisiae, which have not previously been metabolically engineered to produce any valuable, industrially scalable, white biotech commodity.
Functional diversifications of cyanogenic glucosides.
  • B. Møller
  • Biology, Medicine
    Current opinion in plant biology
  • 1 June 2010
TLDR
In plants, cyanogenic glucosides have gained additional functionalities as transporters of nitrogen and operation of an endogenous turnover pathway may enable plants to withdraw the nitrogen and glucose deposited in cyanogenic glucose for use in primary metabolism.
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