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A communication strategy and brochure for relatives of patients dying in the ICU.
TLDR
Providing relatives of patients who are dying in the ICU with a brochure on bereavement and using a proactive communication strategy that includes longer conferences and more time for family members to talk may lessen the burden of bereavement.
Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit.
TLDR
In a trial involving critically ill patients with severe acute kidney injury, a delayed strategy averted the need for renal-replacement therapy in an appreciable number of patients and found no significant difference with regard to mortality.
The tyrosine kinase substrate eps15 is constitutively associated with the plasma membrane adaptor AP-2
TLDR
The results are in keeping with a recent study showing homology between the NH2-terminal domains of eps15 and the product of the gene END3, involved in clathrin-mediated endocytosis of the pheromone alpha factor in Saccharomyces cerevisiae, and suggest a possible role for eps 15 in clATHrin- mediated endocyTosis in mammals.
High versus low blood-pressure target in patients with septic shock.
TLDR
Targeting a mean arterial pressure of 80 to 85 mm Hg, as compared with 65 to 70 mm HG, in patients with septic shock undergoing resuscitation did not result in significant differences in mortality at either 28 or 90 days.
Severe Imported Falciparum Malaria: A Cohort Study in 400 Critically Ill Adults
TLDR
In a large population of adults treated in a non-endemic industrialized country, severe malaria still carried a high mortality rate, and the data, including predictors of death, can probably be generalized to other non- endemic countries where high-quality healthcare is available.
Value of post-resuscitation electrocardiogram in the diagnosis of acute myocardial infarction in out-of-hospital cardiac arrest patients.
TLDR
In patients with OHCA without obvious non-cardiac causes, selection for coronary angiogram based on the combined criterion would detect all AMI and avoid the performance of the procedure in 30% of the patients, in whom coronary angioplasty did not have a therapeutic role.
Postintensive care unit psychological burden in patients with chronic obstructive pulmonary disease and informal caregivers: A multicenter study
TLDR
Psychiatric symptoms were found to be common in a group of 126 patients with chronic obstructive pulmonary disease who survived an intensive care unit stay and their relatives atintensive care unit discharge and 90 days later.
Intravascular Complications of Central Venous Catheterization by Insertion Site.
TLDR
Subclavian-vein catheterization was associated with a lower risk of bloodstream infection and symptomatic thrombosis and a higher risk of pneumothorax than jugular-veins or femoral-veIn catheterized patients.
Synthetic Cathinones: A New Public Health Problem
TLDR
The major clinical effects of synthetic cathinones are reviewed to highlight their impact on public health.
Hydrocortisone plus Fludrocortisone for Adults with Septic Shock
TLDR
In this trial involving patients with septic shock, 90‐day all‐cause mortality was lower among those who received hydrocortisone plus fludrocort isone or with drotrecogin alfa (activated), the combination of the three drugs, or their respective placebos.
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