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von Hippel-Lindau gene-mediated growth suppression and induction of differentiation in renal cell carcinoma cells grown as multicellular tumor spheroids.
- B. Lieubeau-Teillet, J. Rak, S. Jothy, O. Iliopoulos, W. Kälin, R. Kerbel
- Biology, Medicine
- Cancer research
- 1 November 1998
Previous results using gene transfection methods have shown that the wild-type (WT) von Hippel-Lindau (VHL) gene can function as a potent tumor suppressor gene in vivo for renal cell carcinoma (RCC)… Expand