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Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine.
- B. Li, C. Hartono, +7 authors M. Suthanthiran
- The New England journal of medicine
- 29 March 2001
BACKGROUND Acute rejection is a serious and frequent complication of renal transplantation, and its diagnosis is contingent on the invasive procedure of allograft biopsy. A noninvasive diagnostic… Expand
A novel mechanism for telomere size control in Saccharomyces cerevisiae.
One of the central requirements for eukaryotic chromosome stability is the maintenance of the simple sequence tracts at telomeres. In this study, we use genetic and physical assays to reveal the… Expand
Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain…
- B. Li, P. Sehajpal, +4 authors M. Suthanthiran
- Biology, Medicine
- The Journal of experimental medicine
- 1 November 1991
The regulation of mRNA encoding transforming growth factor beta (TGF- beta) and interleukin 2 (IL-2) in normal human T cells was explored using novel competitor DNA constructs in the quantitative… Expand
Identification of mutations in p53 that affect its binding to SV40 large T antigen by using the yeast two‐hybrid system
The tumor suppressor p53 protein binds to the products of several viral oncogenes, including SV40 large T antigen. We reconstructed the p53‐T antigen interaction in the yeast two‐hybrid system, a… Expand
Transcriptional Regulation of the Human DNA Polymerase δ Catalytic Subunit Gene POLD1 by p53 Tumor Suppressor and Sp1*
The DNA polymerase δ catalytic subunit gene (POLD1) was studied as a transcriptional target of p53. Northern blotting showed that a significantly decreased steady-state level of POLD1 mRNA was… Expand
Study of form birefringence in waveguide devices using the semivectorial beam propagation method
Waveguide devices based on nonbirefringent substrates may still have form birefringence if index discontinuities exist. It is demonstrated that the semivectorial beam propagation method can be used… Expand
Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart.
Coronary artery narrowing (CAN) induces tissue injury, which may involve myocyte necrosis and apoptosis. Insulin-like growth factor (IGF)-1 may counteract cell death, modifying the detrimental… Expand
Characterization of the antinociceptive properties of cimetidine and a structural analog.
- B. Li, J. Nalwalk, L. A. Barker, P. Cumming, M. Parsons, L. Hough
- Chemistry, Medicine
- The Journal of pharmacology and experimental…
- 1 February 1996
The antinociceptive and pharmacological properties of the H2 receptor antagonist cimetidine and a novel cimetidine analog, SKF92374, were characterized. On both the hot-plate and tail-flick… Expand
Laser pulse-induced photochemical strand cleavage of site-specifically and covalently modified (+)-anti-benzo[a]pyrene diol epoxide-oligonucleotide adducts.
- B. Li, B. Mao, +4 authors N. Geacintov
- Chemistry, Medicine
- Chemical research in toxicology
- 1 April 1995
The specificity of the laser pulse-induced photocleavage method [Boles, T. C., and Hogan, M. E. (1986) Biochemistry 25, 3039] for detecting the sites of covalent binding of benzo[a]pyrene diol… Expand
Renal allograft surveillance by mRNA profiling of urinary cells.