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Escape from Autologous Neutralizing Antibodies in Acute/Early Subtype C HIV-1 Infection Requires Multiple Pathways
One aim for an HIV vaccine is to elicit neutralizing antibodies (Nab) that can limit replication of genetically diverse viruses and prevent establishment of a new infection. Thus, identifying theExpand
Phosphoinositide-specific phospholipase C9 is involved in the thermotolerance of Arabidopsis.
Intracellular calcium (Ca(2+)) increases rapidly after heat shock (HS) in the Ca(2+)/calmodulin (Ca(2+)/CaM) HS signal transduction pathway: a hypothesis proposed based on our previous findings.Expand
A heat-activated calcium-permeable channel--Arabidopsis cyclic nucleotide-gated ion channel 6--is involved in heat shock responses.
  • Fei Gao, X. Han, +5 authors B. Li
  • Biology, Medicine
  • The Plant journal : for cell and molecular…
  • 1 June 2012
An increased concentration of cytosolic calcium ions (Ca²⁺) is an early response by plant cells to heat shock. However, the molecular mechanism underlying the heat-induced initial Ca²⁺ response inExpand
Calmodulin-binding protein phosphatase PP7 is involved in thermotolerance in Arabidopsis.
PP7 is the first protein Ser/Thr phosphatase to be found to interact with calmodulin (CaM) in plants. The T-DNA insertion AtPP7 knockout line and AtPP7 overexpression lines were employed to study theExpand
The Arabidopsis J-protein AtDjB1 facilitates thermotolerance by protecting cells against heat-induced oxidative damage.
AtDjB1 belongs to the J-protein family in Arabidopsis thaliana. Its biological functions in plants are largely unknown. In this study, we examined the roles of AtDjB1 in resisting heat and oxidativeExpand
Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion.
  • S. Gao, X. Duan, +5 authors B. Li
  • Chemistry, Medicine
  • Food and chemical toxicology : an international…
  • 1 September 2013
Oxidative stress is one of the major mechanisms implicated in inorganic arsenic poisoning. Curcumin is a natural phenolic compound with impressive antioxidant properties. What's more, curcumin isExpand
Molecular immune mechanism of C‐phycocyanin from Spirulina platensis induces apoptosis in HeLa cells in vitro
C‐phycocyanin (C‐PC), a water‐soluble protein pigment, isolated from Spirulina platensis, is of great importance because of its various medical and pharmacological properties. In the present study,Expand
The adjuvant effect induced by di-(2-ethylhexyl) phthalate (DEHP) is mediated through oxidative stress in a mouse model of asthma.
Di-(2-ethylhexyl) phthalate, as the most commonly used plasticizer, is considered to be related to the asthma prevalence. There are studies affirming that the DEHP has an adjuvant effect in theExpand
Ca(2+) and calmodulin modulate DNA-binding activity of maize heat shock transcription factor in vitro.
DNA-binding activity of a maize heat shock transcription factor (HSF) was induced by heat shock of a whole cell extract at 44 degrees C. Addition of the calcium ion chelator EGTA reduced the bindingExpand
THE optimization of HDFS based on small files
HDFS is a distributed file system which can process large amounts of data effectively through large clusters, the HADOOP framework which is based on it has been widely used in various clusters to build large scale, high performance systems. Expand